selected publications
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conference proceeding
- Diminished Endothelial Fibrinolytic Function With Prehypertension. Hypertension. 2013
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Expression of Cardiolipin Biosynthesis and Remodeling Enzymes in Adult Heart Failure.
The Journal of heart transplantation.
S97-S98.
2013
- EXPRESSION OF CARDIOLIPIN BIOSYNTHESIS AND REMODELING ENZYMES IN ADULT HEART FAILURE. Federation proceedings. 2013
- Expression of Cardiolipin Biosynthesis and Remodeling Enzymes in Adult Heart Failure. Journal of Investigative Medicine. 670-670. 2013
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Regulation of beta-Adrenergic Receptors in Pediatric Heart Failure.
Journal of Cardiac Failure.
S40-S41.
2009
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journal article
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Insufficient sleep is associated with a pro-atherogenic circulating microRNA signature..
Experimental Physiology.
975-982.
2019
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Acute isoproterenol leads to age-dependent arrhythmogenesis in guinea pigs.
AJP - Heart and Circulatory Physiology.
H1051-H1062.
2018
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Regular aerobic exercise reduces endothelin-1-mediated vasoconstrictor tone in overweight and obese adults.
Experimental Physiology.
1133-1142.
2017
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Influence of sex on the number of circulating endothelial microparticles and microRNA expression in middle-aged adults.
Experimental Physiology.
894-900.
2017
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Exosomes from pediatric dilated cardiomyopathy patients modulate a pathological response in cardiomyocytes.
AJP - Heart and Circulatory Physiology.
H818-H826.
2017
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Fibrosis and Fibrotic Gene Expression in Pediatric and Adult Patients With Idiopathic Dilated Cardiomyopathy.
Journal of Cardiac Failure.
314-324.
2017
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Molecular Changes in Children with Heart Failure Undergoing Left Ventricular Assist Device Therapy.
Journal of Pediatrics.
184-189.
2017
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Cardiac Adenylyl Cyclase and Phosphodiesterase Expression Profiles Vary by Age, Disease, and Chronic Phosphodiesterase Inhibitor Treatment.
Journal of Cardiac Failure.
72-80.
2017
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Endothelial vasodilator function in normal-weight adults with metabolic syndrome.
Applied Physiology, Nutrition, and Metabolism.
1013-1017.
2016
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Elevations in C-reactive protein and endothelin-1 system activity in humans.
Life Sciences.
66-70.
2016
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Chronic Nebivolol Treatment Suppresses Endothelin-1-Mediated Vasoconstrictor Tone in Adults With Elevated Blood Pressure.
Hypertension.
1196-1204.
2016
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Impaired endogenous fibrinolytic capacity in prehypertensive men.
Journal of Human Hypertension.
468-472.
2015
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Influence of habitual high dietary fat intake on endothelium-dependent vasodilation.
Applied Physiology, Nutrition, and Metabolism.
711-715.
2015
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Transgenic over-expression of YY1 induces pathologic cardiac hypertrophy in a sex-specific manner.
Biochemical and Biophysical Research Communications.
131-137.
2015
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Circulating microRNA as a biomarker for recovery in pediatric dilated cardiomyopathy.
The Journal of heart transplantation.
724-733.
2015
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Diet and sex modify exercise and cardiac adaptation in the mouse.
AJP - Heart and Circulatory Physiology.
H135-H145.
2015
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Age-Related Differences in Phosphodiesterase Activity and Effects of Chronic Phosphodiesterase Inhibition in Idiopathic Dilated Cardiomyopathy.
Circulation: Heart Failure.
57-U112.
2015
- HYPERTROPHY INDUCING FACTOR IN PEDIATRIC IDIOPATHIC DILATED CARDIOMYOPATHY SERUM. Journal of Investigative Medicine. 140-141. 2015
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Micro-RNA Expression in Hypoplastic Left Heart Syndrome.
Journal of Cardiac Failure.
83-88.
2015
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Dysregulation of cardiolipin biosynthesis in pediatric heart failure.
Journal of Molecular and Cellular Cardiology.
251-259.
2014
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ENDOTHELIN-1 SYTEM ACTIVITY IN ADULTS WITH BORDERLINE HIGH LDL-CHOLESTEROL..
Artery Research.
115-118.
2014
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Influence of Dietary Saturated Fat Intake on Endothelial Fibrinolytic Capacity in Adults.
American Journal of Cardiology.
783-788.
2014
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Gene expression and beta-adrenergic signaling are altered in hypoplastic left heart syndrome.
The Journal of heart transplantation.
785-793.
2014
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Metabolic syndrome and endothelin-1 mediated vasoconstrictor tone in overweight/obese adults.
Metabolism.
951-956.
2014
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New Mechanistic and Therapeutic Targets for Pediatric Heart Failure Report From a National Heart, Lung, and Blood Institute Working Group.
Circulation.
79-86.
2014
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Influence of Elevated Levels of C-Reactive Protein on Circulating Endothelial Progenitor Cell Function.
Clinical and Translational Science.
137-140.
2014
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Beta-adrenergic adaptation in paediatric idiopathic dilated cardiomyopathy.
European Heart Journal.
33-41.
2014
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Essential Role of Estrogen for Improvements in Vascular Endothelial Function With Endurance Exercise in Postmenopausal Women.
The Journal of clinical endocrinology.
4507-4515.
2013
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beta-Adrenergic receptor antagonism in mice: a model for pediatric heart disease.
Journal of applied physiology: respiratory, environmental and exercise physiology.
979-987.
2013
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Impaired fasting blood glucose is associated with increased endothelin-1 vasoconstrictor tone.
Atherosclerosis.
130-133.
2013
- Metabolic Syndrome and Endothelin-1 mediated vasoconstrictor tone in overweight/obese adults. Federation proceedings. 2013
- Short Sleep Duration and Endothelial t-PA Release in Overweight/Obese Adults. Federation proceedings. 2013
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miRNA expression in pediatric failing human heart.
Journal of Molecular and Cellular Cardiology.
43-46.
2013
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Self-Reported Habitual Short Sleep Duration Is Associated with Endothelial Fibrinolytic Dysfunction in Men: A Preliminary Report.
SLEEP.
183-188.
2013
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Estrogenic Compounds Are Not Always Cardioprotective and Can Be Lethal in Males with Genetic Heart Disease.
Endocrinology.
4470-4479.
2012
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Hysterectomy is associated with large artery stiffening in estrogen-deficient postmenopausal women.
Menopause.
1000-1007.
2012
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White blood cell count and endothelin-1 vasoconstrictor tone in middle-aged and older adults..
Artery Research.
65-70.
2012
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Elevated Endothelin-1 Vasoconstrictor Tone in Prehypertensive Adults.
Canadian Journal of Cardiology.
347-353.
2012
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Nitric Oxide-Mediated Endothlium-Dependent Vasodilation Is Impaired with Borderline High-LDL Cholesterol.
Clinical and Translational Science.
21-26.
2012
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Relation of C-Reactive Protein to Endothelial Fibrinolytic Function in Healthy Adults.
American Journal of Cardiology.
1675-1679.
2011
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CD31(+) T Cells, Endothelial Function and Cardiovascular Risk.
Heart, Lung and Circulation.
659-662.
2011
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Enhanced endothelin-1 system activity with overweight and obesity.
AJP - Heart and Circulatory Physiology.
H689-H695.
2011
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Influence of Abdominal Obesity on Vascular Endothelial Function in Overweight/Obese Adult Men.
Obesity Research.
1742-1746.
2011
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Prehypertension Is Associated With Impaired Nitric Oxide-Mediated Endothelium-Dependent Vasodilation in Sedentary Adults.
American Journal of Hypertension.
976-981.
2011
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Sex Differences in Cardiomyocyte Connexin43 Expression.
Journal of Cardiovascular Pharmacology.
32-39.
2011
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Endothelin-I vasoconstriction and the age-related decline in endothelium-dependent vasodilatation in men.
Clinical Science.
485-491.
2011
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Remodeling the cardiac transcriptional landscape with diet.
Physiological Genomics.
772-780.
2011
- C-Reactive Protein-Related Endothelial Vasodilator Dysfunction in Healthy Adults. Federation proceedings. 2011
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Habitual short sleep duration and circulating endothelial progenitor cells..
Journal of Cardiovascular Disease Research.
110-114.
2011
- Impaired Nitric Oxide Mediated Endothelium-Dependent Vasodilation with Suboptimal LDL Cholesterol. Federation proceedings. 2011
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Aging Is Associated with a Proapoptotic Endothelial Progenitor Cell Phenotype.
Journal of Vascular Research.
408-414.
2011
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Prehypertension and endothelial progenitor cell function.
Journal of Human Hypertension.
57-62.
2011
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Human aging and CD31(+) T-cell number, migration, apoptotic susceptibility, and telomere length.
Journal of applied physiology: respiratory, environmental and exercise physiology.
1756-1761.
2010
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Endothelial Progenitor Cell Function, Apoptosis, and Telomere Length in Overweight/Obese Humans.
Obesity Research.
1677-1682.
2010
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Osteopenia and endothelin-1-mediated vasconstrictor tone in postmenopausal women.
BONE.
542-545.
2010
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Regular Aerobic Exercise, Without Weight Loss, Improves Endothelium-dependent Vasodilation in Overweight and Obese Adults.
Obesity Research.
1667-1669.
2010
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Short sleep duration is associated with enhanced endothelin-1 vasoconstrictor tone.
Canadian Journal of Physiology and Pharmacology.
777-781.
2010
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Epigenetics: an emerging player in health and disease.
Journal of applied physiology: respiratory, environmental and exercise physiology.
230-231.
2010
- Influence of Aging on Angiogenic T cells. Federation proceedings. 2010
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Ageing and endothelial progenitor cellrelease of proangiogenic cytokines.
Age and Ageing.
268-272.
2010
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Sex differences in endothelin-1-mediated vasoconstrictor tone in middle-aged and older adults.
AJP - Regulatory, Integrative and Comparative Physiology.
R261-R265.
2010
- Endothelial Tissue-Type Plasminogen Activator Release Is Reduced in Older Adults with Metabolic Syndrome. Circulation. E291-E292. 2009
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Endothelial progenitor cell number and colony-forming capacity in overweight and obese adults.
International Journal of Obesity.
219-225.
2009
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Aging and endothelial progenitor cell telomere length in healthy men.
Clinical Chemistry and Laboratory Medicine.
47-50.
2009
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Transcriptional Regulation of beta(2)-Microglobulin Demonstrated Via a Novel Genomic and Proteomic Analysis of Percutaneously Collected Peripheral Atheroma.
Clinical and Translational Science.
240-244.
2008
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Gender and Endothelial Progenitor Cell Number in Middle-Aged Adults..
Artery Research.
156-160.
2008
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Acute and chronic effects of vitamin C on endothelial fibrinolytic function in overweight and obese adult humans.
Journal of Physiology.
3525-3535.
2008
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Endothelin-1, aging and hypertension.
Current Opinion in Cardiology.
350-355.
2008
- Influence of adiposity on endothelial progenitor cell number and clonogenic capacity. Arteriosclerosis, Thrombosis, and Vascular Biology. E145-E145. 2008
- Prehypertension and endothelial progenitor cell function. Arteriosclerosis, Thrombosis, and Vascular Biology. E146-E146. 2008
- Shortened telomere length in endothelial progenitor cells with age. Arteriosclerosis, Thrombosis, and Vascular Biology. E105-E105. 2008
- Aging and EPC Release of Proangiogenic Factors. Federation proceedings. 2008
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Impaired endothelium-dependent vasodilation in overweight and obese adult humans is not limited to muscarinic receptor agonists.
AJP - Heart and Circulatory Physiology.
H1685-H1692.
2008
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Metabolic syndrome and endothelial fibrinolytic capacity in obese adults.
AJP - Regulatory, Integrative and Comparative Physiology.
R39-R44.
2008
- Feasibility of molecular analysis of percutaneously collected peripheral atheroma. American Journal of Cardiology. 83L-83L. 2007
- Plant estrogens in the rodent diet negatively impact genetic heart disease in males. Circulation Research. E65-E66. 2007
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Endothelin-1 vasoconstrictor tone increases with age in healthy men but can be reduced by regular aerobic exercise.
Hypertension.
403-409.
2007
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Aging, exercise, and endothelial progenitor cell clonogenic and migratory capacity in men.
Journal of applied physiology: respiratory, environmental and exercise physiology.
847-852.
2007
- Aging, exercise, and endothelial progenitor cell apoptosis. Circulation. E251-E251. 2007
- Endothelin-1 vasoconstrictor activity contributes to impaired acetylcholine-mediated vasodilation in obesity. Circulation. E242-E242. 2007
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Gender differences in circulating endothelial progenitor cell colony-forming capacity and migratory activity in middle-aged adults.
American Journal of Cardiology.
46-48.
2007
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Influence of metabolic syndrome on biomarkers of oxidative stress and inflammation in obese adults.
Obesity Research.
2127-2131.
2006
- Greater oxidative stress and inflammatory burden in obese adults with the metabolic syndrome. Arteriosclerosis, Thrombosis, and Vascular Biology. E84-E85. 2006
- Regular aerobic exercise alleviates the age-related increase in endothelin-1 mediated vasoconstrictor tone. Arteriosclerosis, Thrombosis, and Vascular Biology. E99-E99. 2006
- Vitamin C supplementation improves endothelial t-PA release in obese adults. Arteriosclerosis, Thrombosis, and Vascular Biology. E103-E103. 2006
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Exercise can prevent and reverse the severity of hypertrophic cardiomyopathy.
Circulation Research.
540-548.
2006
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Impaired endothelium-dependent vasodilation in normotensive and normoglycemic obese adult humans.
Journal of Cardiovascular Pharmacology.
310-313.
2006
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Soy diet worsens heart disease in mice.
Journal of Clinical Investigation.
209-216.
2006
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Endothelial t-PA release is impaired in overweight and obese adults but can be improved with regular aerobic exercise.
AJP - Endocrinology and Metabolism.
E807-E813.
2005
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Basal endothelial nitric oxide release is preserved in overweight and obese adults.
Obesity Research.
1303-1306.
2005
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Estrogen receptor-alpha thymidine and adenine repeat polymorphism and endothelial fibrinolytic regulation in postmenopausal women.
American Journal of Obstetrics and Gynecology.
366-370.
2005
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Gender differences in endothelial tissue-type plasminogen activator release in middle-aged adults.
Journal of the American College of Cardiology.
1547-1549.
2005
- Beneficial effects of exercise on age-related reductions in endothelial progenitor cell number and migratory activity. Arteriosclerosis, Thrombosis, and Vascular Biology. E50-E50. 2005
- Estrogen receptor-alpha polymorphism and endothelial fibrinolytic regulation in postmenopausal women. Circulation. E51-E51. 2005
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Sex modifies exercise and cardiac adaptation in mice.
AJP - Heart and Circulatory Physiology.
H2768-H2776.
2004
- Impaired acetylcholine-mediated vasodilation in obesity is not due to reduced responsiveness or increased cholinesterase activity. Arteriosclerosis, Thrombosis, and Vascular Biology. E16-E16. 2004
- Impaired endothelial fibrinolytic capacity with obesity is associated with oxidative stress. Arteriosclerosis, Thrombosis, and Vascular Biology. E40-E40. 2004
- Exercise without weight loss does not lower plasma C-reactive protein in obese adults. Federation proceedings. A1297-A1297. 2004
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Morphological and functional alterations in ventricular myocytes from male transgenic mice with hypertrophic cardiomyopathy.
Circulation Research.
201-207.
2004
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Plasma C-reactive protein is not elevated in physically active postmenopausal women taking hormone replacement therapy.
Journal of applied physiology: respiratory, environmental and exercise physiology.
143-148.
2004
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Acute and chronic effects of oestrogen on endothelial tissue-type plasminogen activator release in postmenopausal women.
Journal of Physiology.
721-728.
2003
-
Endothelial release of tissue-type plasminogen activator in the human forearm: Role of nitric oxide.
Journal of Cardiovascular Pharmacology.
311-314.
2003
- Obesity-related impairment in endothelial t-PA release is reversed with exercise. Arteriosclerosis, Thrombosis, and Vascular Biology. A22-A22. 2003
- Postmenopausal hormone replacement therapy and endothelial fibrinolytic capacity. Arteriosclerosis, Thrombosis, and Vascular Biology. A8-A9. 2003
- Plasma C-reactive protein is not elevated in physically active postmenopausal women taking hormone replacement therapy. Journal of the American College of Cardiology. 283A-283A. 2003
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Short-term triglyceride lowering with fenofibrate improves vasodilator function in subjects with hypertriglyceridemia.
Arteriosclerosis, Thrombosis, and Vascular Biology.
307-313.
2003
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Effects of ageing and regular aerobic exercise on endothelial fibrinolytic capacity in humans.
Journal of Physiology.
289-298.
2003
-
Effects of ageing and regular aerobic exercise on endothelial fibrinolytic capacity in humans.
Journal of Physiology.
289-298.
2003
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Influence of oral contraceptive use on endothelial t-PA release in healthy premenopausal women.
AJP - Endocrinology and Metabolism.
E90-E95.
2003
- Age and gender-associated gene expression profiles in a mouse model of hypertrophic cardiomyopathy. Circulation. 208-208. 2002
- Regular aerobic exercise prevents and reverses the age-related decline in endothelial t-PA release. Circulation. 615-615. 2002
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Evidence for agonist-specific endothelial vasodilator dysfunction with ageing in healthy humans.
Journal of Physiology.
255-262.
2002
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Evidence for agonist-specific endothelial vasodilator dysfunction with ageing in healthy humans.
Journal of Physiology.
255-262.
2002
- Capacity of the vascular endothelium to release tissue-type plasminogen activator declines with age in healthy adult humans. Federation proceedings. A436-A436. 2002
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From sarcomeric mutations to heart disease: Understanding familial hypertrophic cardiomyopathy.
Cold Spring Harbor Symposia on Quantitative Biology.
409-415.
2002
-
Reductions in basal limb blood flow and vascular conductance with human ageing: role for augmented alpha-adrenergic vasoconstriction.
Journal of Physiology.
977-983.
2001
-
Reductions in basal limb blood flow and vascular conductance with human ageing: role for augmented alpha-adrenergic vasoconstriction.
Journal of Physiology.
977-983.
2001
- Sex hormones influence the phenotype of hypertrophic cardiomyopathy in a transgenic mouse model. Circulation. 308-308. 2001
- Triglyceride lowering with fenofibrate improves endothelial vasodilator function in patients with hypertriglyceridemia. Circulation. 240-240. 2001
- Impaired endothelial vasodilator response to muscarinic but not beta-adrenoceptor stimulation in older men. Federation proceedings. A1127-A1127. 2001
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Endurance exercise alters the contractile responsiveness of rat heart to extracellular Na+ and Ca2+.
Medicine and science in sports.
1502-1509.
1998
- Hypertension alters rapid cooling contractures in single rat cardiocytes. American Journal of Physiology - Cell Physiology. C1000-C1006. 1997
- Hypertension alters rapid cooling contractures in single rat cardiocytes.. American Journal of Physiology. C1000-C1006. 1997
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Insufficient sleep is associated with a pro-atherogenic circulating microRNA signature..
Experimental Physiology.
975-982.
2019