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Tan, Zhongping Assistant Professor

Positions

Research Areas research areas

Research

research overview

  • Dr. Tan uses an chemical glycobiology approach to study the glycosylation of industrial enzymes and therapeutic proteins. Protein glycosylation is an important post-translational modification. It enhances the functional diversity of proteins. However, because of the complex and variable nature of glycans attached to proteins, establishing quantitative relationships between glycan structures and their functions is difficult. The novel component of Dr. Tan’s research program is that they use chemical biology as a tool to study protein glycosylation. As compared to other available approaches, chemical synthesis is a more flexible and precise means by which to accomplish glycan structural modifications and amino acid mutations. This enables Dr. Tan and his co-workers to develop a better understanding of protein glycosylation, which in turn make it possible for them to develop enzymes and protein-based therapeutics with improved properties through glycoengineering.

keywords

  • chemical glycobiochemistry/glycobiology, chemical glycoproteomics, carbohydrate chemistry, peptide chemistry, peptide/protein glycoengineering

Publications

selected publications

Teaching

courses taught

  • CHEM 3311 - Organic Chemistry 1
    Primary Instructor - Fall 2018
    Lect. and rec. Intended primarily for nonmajors. Topics include structure and reactions of alkanes, alkenes, alkynes, alkyl halides, and aromatic molecules; nomenclature of organic compounds; stereochemistry; reaction mechanisms and dynamics. Department enforced corequisite: CHEM 3321 or CHEM 3361.
  • CHEM 6901 - Research in Chemistry
    Primary Instructor - Spring 2018 / Summer 2018 / Fall 2018 / Spring 2019 / Summer 2019
    May be repeated up to 15 total credit hours.

Background

International Activities

global connections related to teaching and scholarly work (in recent years)

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