selected publications

• conference proceeding

  • Analysis of significant protein abundance from multiple reaction-monitoring data.  BMC Systems Biology. 2018
  • Detecting population structures by independent component analysis.  Proceedings. IEEE International Conference on Bioinformatics and Biomedicine. 1784-1787. 2018
  • HisCoM-GGI: Hierarchical structural component analysis of gene-gene interactions.  Journal of Bioinformatics and Computational Biology. 2018
  • Topological data analysis can extract subgroups with high incidence rates of Type 2 diabetes.  Proceedings. IEEE International Conference on Bioinformatics and Biomedicine. 1758-1758. 2018
  • Meta-Qtest: meta-analysis of quadratic test for rare variants.  BMC Medical Genomics. 2018
  • Pathway analysis of rare variants for the clustered phenotypes by using hierarchical structured components analysis.  BMC Medical Genomics. 2018
  • Hierarchical structural component modeling of microRNA-mRNA integration analysis.  BMC Bioinformatics. 2018
  • Pathway-based approach using hierarchical components of rare variants to analyze multiple phenotypes.  BMC Bioinformatics. 2018
  • Association Study of Melatonin Pathway Genes With Seasonality and Circadian Preference in Bipolar Disorder.  Biological Psychiatry. S288-S288. 2017
  • Genetic Variations Within Acyl-CoA Synthetase Bubblegum Family Member 1(ACSBG1) Gene Showed a Genome-Widely Significant Association With a Phenotype Dimension Characterized by Bulimic and Anxiety Comorbidities in Subjects With Bipolar Disorders.  Biological Psychiatry. S289-S289. 2017
  • Qualify Control Plot for High Dimensional Omics Data.  Proceedings. IEEE International Conference on Bioinformatics and Biomedicine. 1763-1766. 2016
  • Developing cancer prediction model based on stepwise selection by AUC measure for proteomics data.  Proceedings. IEEE International Conference on Bioinformatics and Biomedicine. 1345-1350. 2015
  • VizEpis : A visualization and mapping tool for interpreting epistasis.  Proceedings. IEEE International Conference on Bioinformatics and Biomedicine. 1363-1366. 2015
  • Biomarker development for pancreatic ductal adenocarcinoma using integrated analysis of mRNA and miRNA expression.  Proceedings. IEEE International Conference on Bioinformatics and Biomedicine. 2014
  • Identifying differentially expressed genes for ordinal phenotypes.  Proceedings. IEEE International Conference on Bioinformatics and Biomedicine. 2014

• journal article

  • Diagnostic model for pancreatic cancer using a multi-biomarker panel.  Annals of surgical treatment and research. 144-153. 2021
  • HisCoM-PAGE: Hierarchical Structural Component Models for Pathway Analysis of Gene Expression Data.  Genes. 2019
  • Psychopathologic structure of bipolar disorders: exploring dimensional phenotypes, their relationships, and their associations with bipolar I and II disorders.  Psychological Medicine. 2177-2185. 2019
  • Exploratory analysis for detecting population structures by iterative pruning based on independent component analysis.  International Journal of Data Mining and Bioinformatics. 61-74. 2019
  • Topological data analysis can extract sub-groups with high incidence rates of Type 2 diabetes.  International Journal of Data Mining and Bioinformatics. 44-60. 2019
  • Unified Cox model based multifactor dimensionality reduction method for gene-gene interaction analysis of the survival phenotype.  BioData Mining. 2018
  • New Common and Rare Variants Influencing Metabolic Syndrome and Its Individual Components in a Korean Population.  Scientific Reports. 2018
  • Sequence data and association statistics from 12,940 type 2 diabetes cases and controls (vol 4, 170179, 2017).  Scientific Data. 2018
  • Diagnostic performance enhancement of pancreatic cancer using proteomic multimarker panel (vol 8, pg 93117, 2017).  Oncotarget. 5514-5514. 2018
  • Effects of genetic variants of &ITST8SIA2&IT and &ITNCAM1&IT genes on seasonal mood changes and circadian preference in the general population.  Chronobiology International: the journal of biological and medical rhythm research. 405-415. 2018
  • Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.  Scientific Data. 2017
  • Proposed Nomogram Predicting the Individual Risk of Malignancy in the Patients With Branch Duct Type Intraductal Papillary Mucinous Neoplasms of the Pancreas.  Annals of Surgery. 1062-1068. 2017
  • Diagnostic performance enhancement of pancreatic cancer using proteomic multimarker panel.  Oncotarget. 93117-93130. 2017
  • Serum fibronectin distinguishes the early stages of hepatocellular carcinoma.  Scientific Reports. 2017
  • Long-term response to mood stabilizer treatment and its clinical correlates in patients with bipolar disorders: a retrospective observational study.  International Journal of Bipolar Disorders. 2017
  • Association between the zinc finger protein 804A (ZNF804A) gene and the risk of schizophrenia and bipolar I disorder across diagnostic boundaries.  Bipolar Disorders: an international journal of psychiatry and neurosciences. 305-313. 2017
  • Ceruloplasmin as a prognostic marker in patients with bile duct cancer.  Oncotarget. 29028-29037. 2017
  • Rare variant association test with multiple phenotypes.  Genetic Epidemiology. 198-209. 2017
  • Integrative analysis of multi-omics data for identifying multi-markers for diagnosing pancreatic cancer (vol 16, S4, 2015).  BMC Genomics. 2017
  • Calibration of High-Density Lipoprotein Cholesterol Values From the Korea National Health and Nutrition Examination Survey Data, 2008 to 2015.  Annals of laboratory medicine. 1-8. 2017
  • Statistical quality control analysis of high-dimensional omics data.  International Journal of Data Mining and Bioinformatics. 210-222. 2017
  • Using the Generalized Index of Dissimilarity to Detect Gene-Gene Interactions in Multi-Class Phenotypes.  PLoS One. 2016
  • The genetic architecture of type 2 diabetes.  Nature. 41-+. 2016
  • A Model-Based Joint Identification of Differentially Expressed Genes and Phenotype-Associated Genes.  PLoS One. 2016
  • Biomarker Development for Intraductal Papillary Mucinous Neoplasms Using Multiple Reaction Monitoring Mass Spectrometry.  Journal of Proteome Research. 100-113. 2016
  • Comparative studies for developing protein based cancer prediction model to maximise the ROC-AUC with various variable selection methods.  International Journal of Data Mining and Bioinformatics. 64-76. 2016
  • beta-Caryophyllene potently inhibits solid tumor growth and lymph node metastasis of B16F10 melanoma cells in high-fat diet-induced obese C57BL/6N mice.  Carcinogenesis. 1028-1039. 2015
  • Integrative analysis of multi-omics data for identifying multi-markers for diagnosing pancreatic cancer.  BMC Genomics. 2015
  • Robust Gene-Gene Interaction Analysis in Genome Wide Association Studies.  PLoS One. 2015
  • A Comparative Study on Multifactor Dimensionality Reduction Methods for Detecting Gene-Gene Interactions with the Survival Phenotype.  BioMed Research International. 2015
  • Benzyl Isothiocyanate Suppresses High-Fat Diet-Stimulated Mammary Tumor Progression via the Alteration of Tumor Microenvironments in Obesity-Resistant BALB/c Mice.  Molecular Carcinogenesis. 72-82. 2015
  • Manikin Families Representing Obese Airline Passengers in the US.  Journal of Healthcare Engineering. 479-504. 2014
  • Practical Issues in Screening and Variable Selection in Genome-Wide Association Analysis.  Cancer Informatics. 55-65. 2014