Antineoplastic Agents
PubMed MeSh Term
Overview
subject area of
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3 '-azidothymidine significantly alters glycosphingolipid synthesis in melanoma cells and decreases the shedding of gangliosides Journal Article
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A redox pathway leading to the alkylation of nucleic acids by doxorubicin and related anthracyclines: Application to the design of antitumor drugs for resistant cancer Journal Article
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Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling Journal Article
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Analysis of Mitosis and Antimitotic Drug Responses in Tumors by In Vivo Microscopy and Single-Cell Pharmacodynamics Journal Article
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Anti-EGFR Affibodies with Site-Specific Photo-Cross-Linker Incorporation Show Both Directed Target-Specific Photoconjugation and Increased Retention in Tumors Journal Article
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Antibodies Predict Pegaspargase Allergic Reactions and Failure of Rechallenge. Journal Article
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Antiestrogen binding site and estrogen receptor mediate uptake and distribution of 4-hydroxytamoxifen-targeted doxorubicin-formaldehyde conjugate in breast cancer cells. Journal Article
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Carboxylesterase-2 is a highly sensitive target of the antiobesity agent orlistat with profound implications in the activation of anticancer prodrugs Journal Article
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Cell death when the SAC is out of commission Journal Article
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Chemical ionization mass spectrometric determination of acrolein in human breast cancer cells Journal Article
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Crystal structure of epidoxorubicin-formaldehyde virtual crosslink of DNA and evidence for its formation in human breast-cancer cells Journal Article
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Design, synthesis, and biological evaluation of doxorubicin - Formaldehyde conjugates targeted to breast cancer cells Journal Article
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Design, synthesis, and preliminary evaluation of doxazolidine carbamates as prodrugs activated by carboxylesterases Journal Article
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Dietary phytoestrogens present in soy dramatically increase cardiotoxicity in male mice receiving a chemotherapeutic tyrosine kinase inhibitor Journal Article
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Doxazolidine induction of apoptosis by a topoisomerase II independent mechanism Journal Article
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Doxorubicin-formaldehyde conjugate, Doxoform: Induction of apoptosis relative to doxorubicin Journal Article
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Enzymes Photo-Cross-Linked to Live Cell Receptors Retain Activity and EGFR Inhibition after Both Internalization and Recycling Journal Article
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Growth inhibition, nuclear uptake, and retention of anthracycline-formaldehyde conjugates in prostate cancer cells relative to clinical anthracyclines Journal Article
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Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf(V600E) kinase Journal Article
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Histone Parylation factor 1 contributes to the inhibition of PARP1 by cancer drugs Journal Article
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Human Embryonic Stem Cell-Derived Keratinocytes Exhibit an Epidermal Transcription Program and Undergo Epithelial Morphogenesis in Engineered Tissue Constructs Journal Article
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Identification of human intestinal carboxylesterase as the primary enzyme for activation of a doxazolidine carbamate prodrug Journal Article
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Inhibition of c-Kit signaling is associated with reduced heat and cold pain sensitivity in humans Journal Article
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Inhibition of exportin-1 function results in rapid cell cycle-associated DNA damage in cancer cells Journal Article
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Introduction to Cancer Chemotherapeutics Journal Article
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Lack of glutathione conjugation to adriamycin in human breast cancer MCF-7/DOX cells - Inhibition of glutathione S-transferase P1-1 by glutathione conjugates from anthracyclines Journal Article
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Linking long noncoding RNA to drug resistance Journal Article
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Longitudinal tracking of single live cancer cells to understand cell cycle effects of the nuclear export inhibitor, selinexor Journal Article
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Loss of p53 expression in cancer cells alters cell cycle response after inhibition o f exportin-1 but does not prevent cell death Journal Article
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Mass spectrometric measurement of formaldehyde generated in breast cancer cells upon treatment with anthracycline antitumor drugs Journal Article
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Multifunctional nanoclusters of NaYF4:Yb3+,Er3+ upconversion nanoparticle and gold nanorod for simultaneous imaging and targeted chemotherapy of bladder cancer Journal Article
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Nuclear targeting and nuclear retention of anthracycline-formaldehyde conjugates implicates DNA covalent bonding in the cytotoxic mechanism of anthracyclines Journal Article
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PEG-peptide hydrogels reveal differential effects of matrix microenvironmental cues on melanoma drug sensitivity Journal Article
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Partitioning of cancer therapeutics in nuclear condensates. Journal Article
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Phosphatase inhibition leads to histone deacetylases 1 and 2 phosphorylation and disruption of corepressor interactions Journal Article
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Preclinical Efficacy of a Carboxylesterase 2-Activated Prodrug of Doxazolidine Journal Article
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REDOX CHEMISTRY OF ANTHRACYCLINE ANTITUMOR DRUGS AND USE OF CAPTODATIVE RADICALS AS TOOLS FOR ITS ELUCIDATION AND CONTROL Journal Article
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Rational design and synthesis of androgen receptor-targeted nonsteroidal anti-androgen ligands for the tumor-specific delivery of a doxorubicin-formaldehyde conjugate Journal Article
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Redox pathway leading to the alkylation of DNA by the anthracycline, antitumor drugs adriamycin and daunomycin Journal Article
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Screening for Radiation Sensitizers of Drosophila Checkpoint Mutants Journal Article
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Side Population Cells from Human Melanoma Tumors Reveal Diverse Mechanisms for Chemoresistance Journal Article
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Single-Agent Inhibition of Chk1 Is Antiproliferative in Human Cancer Cell Lines In Vitro and Inhibits Tumor Xenograft Growth In Vivo Journal Article
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Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin Journal Article
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Synthesis and Biological Activities of Azalamellarins Journal Article
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Synthesis and Biological Characterization of Protease-Activated Prodrugs of Doxazolidine Journal Article
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The RNase PARN Controls the Levels of Specific miRNAs that Contribute to p53 Regulation Journal Article
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Through the Looking Glass: Time-lapse Microscopy and Longitudinal Tracking of Single Cells to Study Anti-cancer Therapeutics Journal Article
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Toward the Rational Design of p53-Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant Journal Article
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WATER-SOLUBLE 3RD GENERATION ANTITUMOR PLATINUM COMPLEXES, [2,2-BIS(AMINOMETHYL)-1,3-PROPANEDIOL-N,N']-[1,1-CYCLOBUTANEDICARBOXYLATO(2-)-O,O']PLATINUM(II) AND [1,1-CYCLOBUTANEDICARBOXYLATO(2-)-O,O'][TETRAHYDRO-4H-PYRAN-4,4-DIMETHANAMINE-N,N']PLATINUM(II)3 Journal Article
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XPB, a subunit of TFIIH, is a target of the natural product triptolide Journal Article
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beta-Caryophyllene potently inhibits solid tumor growth and lymph node metastasis of B16F10 melanoma cells in high-fat diet-induced obese C57BL/6N mice Journal Article
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