Aging and a Peripheral Immune Challenge Interact to Reduce Mature Brain-Derived Neurotrophic Factor and Activation of TrkB, PLC gamma 1, and ERK in Hippocampal Synaptoneurosomes
Journal Article
Overview
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Aging
Animals
Biochemical Phenomena - Phosphorylation
Biochemical Phenomena - Signal Transduction
Biological Factors - Brain-Derived Neurotrophic Factor
Biological Factors - Interleukin 1 Receptor Antagonist Protein
Cell Physiological Phenomena - Signal Transduction
Cerebral Cortex - Hippocampus
Chemistry Techniques, Analytical - Blotting, Western
Electrochemical Techniques - Blotting, Western
Escherichia coli Infections
Immunologic Techniques - Blotting, Western
Limbic System - Hippocampus
Male
Metabolism - Phosphorylation
Molecular Probe Techniques - Blotting, Western
Molecular Probe Techniques - Blotting, Western
Nerve Tissue Proteins - Brain-Derived Neurotrophic Factor
Organic Chemistry Phenomena - Phosphorylation
Peptides - Brain-Derived Neurotrophic Factor
Peptides - Extracellular Signal-Regulated MAP Kinases
Peptides - Interleukin 1 Receptor Antagonist Protein
Peptides - Phospholipase C gamma
Protein-Serine-Threonine Kinases - Extracellular Signal-Regulated MAP Kinases
Protein-Tyrosine Kinases - Receptor, trkB
Proteins - Brain-Derived Neurotrophic Factor
Proteins - Extracellular Signal-Regulated MAP Kinases
Proteins - Interleukin 1 Receptor Antagonist Protein
Proteins - Phospholipase C gamma
Rats
Receptor, Nerve Growth Factor
Receptors, Cell Surface - Receptor, trkB
Receptors, Nerve Growth Factor - Receptor, trkB
Synaptosomes
Type C Phospholipases - Phospholipase C gamma
Full Author List
Cortese GP; Barrientos RM; Maier SF; Patterson SL
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