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Whiteley, Aaron

Assistant Professor

Positions

Research Areas research areas

Research

research overview

  • Pathogens, such as viruses and bacteria, can infect a wide range of hosts to replicate and cause disease. Hosts respond to these invaders with their immune systems. Whether the pathogen is a virus infecting human cell, or a virus that infects bacteria (a phage), the immune system represent a barrier to pathogen replication. Our lab studies the interplay between hosts and their pathogens. The ultimate goal of our work is to better understand infectious diseases to enable development the next generation of therapeutics.

keywords

  • cGAS-STING, NLRs, innate immunity, phage biology, bacterial antagonism

Publications

selected publications

Teaching

courses taught

  • BCHM 4740 - Biochemistry of Gene Transmission, Expression and Regulation
    Primary Instructor - Fall 2023
    Covers biosynthesis and function of macromolecules including DNA, RNA and proteins; molecular basis of replication, transcription and translation; biochemistry of subcellular systems; signaling and regulation of gene expression in eukaryotes; and special topics. Formerly CHEM 4740. Same as BCHM 5740.
  • BCHM 5770 - Fundamentals of Biochemistry I
    Primary Instructor - Fall 2022
    Analysis of topics in biochemistry including DNA structure and replication, RNA synthesis and processing, protein synthesis, enzyme function and mechanism, and protein structure and dynamics. Intended as a comprehensive treatment of areas central to modern biochemistry for entering graduate students. Lectures concurrent with BCHM 5771 covering the same topics except for the requirement of a written research proposal. Formerly CHEM 5770.
  • BCHM 5771 - Advanced General Biochemistry 1
    Primary Instructor - Fall 2020 / Fall 2021 / Fall 2022
    Lect. In-depth analysis of DNA structure and replication, RNA synthesis and processing, protein synthesis, enzyme function and mechanism, protein structure, protein dynamics, and physical chemistry of macromolecules. Intended as a comprehensive treatment of areas central to modern biochemistry for entering graduate students. Formerly CHEM 5771.
  • BCHM 5776 - Scientific Ethics and Responsible Conduct in Research
    Primary Instructor - Fall 2020 / Fall 2021 / Fall 2022
    Lect. Advanced discussion of topics in scientific ethics, including requirements for responsible conduct of research, case histories of fraud, research misconduct, ethical misconduct and development of professional values and ethical standards. Same as MCDB 5776.
  • BCHM 6901 - Research in Biochemistry
    Primary Instructor - Fall 2020 / Spring 2021 / Fall 2021 / Spring 2022 / Fall 2022 / Spring 2023
    May be repeated up to 15 total credit hours.
  • MCDB 6000 - Introduction to Laboratory Methods
    Primary Instructor - Fall 2022 / Spring 2023
    Introduces methodology and techniques used in biological research. Designed as a tutorial between a few students and one faculty member. Students are expected to read original research papers, discuss findings, and to plan and execute experiments in selected areas. May be repeated up to 15 total credit hours.

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