• Contact Info
Publications in VIVO
 

Xue, Ding Professor

Positions

Research Areas research areas

Research

research overview

  • Dr. Xue's research interests lie in studying the mechanisms of programmed cell death (or apoptosis), phospholipid asymmetry in biological membranes, mitochondrial inheritance, and radiation-induced bystander effects, as well as various human diseases associated with abnormalities in these fundamental biological processes. His laboratory has been using molecular genetic, biochemical, cell biological, pharmacological, and structural biological approaches to study the mechanisms that regulate and execute these important cellular and developmental processes in the nematode C. elegans and in mammals. Dr. Xue’s group also uses C. elegans as an animal model to study and carry out drug discovery to treat human diseases, including cancer, hepatitis B virus, and neurodegenerative disease.

keywords

  • apoptosis, necrosis, genetics, developmental biology, lipid asymmetry, hepatitis B virus, mitochondrial and ER signaling, mitochondrial inheritance, drug screens, biochemistry, cell biology, genome editing, radiation-induced bystander effects, neurodegenerative disorders, & stress response

Publications

selected publications

Teaching

courses taught

  • MCDB 4426 - Cell Signaling and Developmental Regulation
    Primary Instructor - Spring 2018 / Spring 2019 / Spring 2020 / Spring 2021
    Introduces several cell signaling processes and their biological functions. Students read and analyze original research articles to learn the thinking processes of scientific research. Writing assignments and oral presentations are required. Fulfills MCDB scientific reasoning requirement. Recommended prerequisites: MCDB 3135 and MCDB 3145 and CHEM 4700 (minimum grade C-). Same as MCDB 5426.
  • MCDB 4990 - Honors Thesis
    Primary Instructor - Spring 2020
    Involves the preparation and defense of an honors thesis, based on faculty-supervised original research, including final phases of the research project. Recommended prerequisites: MCDB 4840 or MCDB 4980 or comparable research experience, and minimum GPA of 3.3 and approval by the MCDB Honors Committee.
  • MCDB 5426 - Cell Signaling and Developmental Regulation
    Primary Instructor - Spring 2018 / Spring 2019 / Spring 2020 / Spring 2021
    Introduces several cell signaling processes and their biological functions. Students read and analyze original research articles to learn the thinking processes of scientific research. Writing assignments and oral presentations are required. Same as MCDB 4426.

Background

awards and honors

International Activities

Other Profiles