The Arnoult lab focuses on genome stability, DNA repair and telomere biology. We study the different types of pathways that cells use to repair DNA double strand breaks, and how telomeres escape these repair mechanisms. We are particularly interested in the mechanisms that control repair pathway selection, in link with cancer and aging.
MCDB 3135 - Molecular Cell Biology I
Primary Instructor
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Fall 2019 / Fall 2020 / Fall 2021 / Spring 2022 / Fall 2022 / Spring 2023 / Fall 2023 / Spring 2024
Examines the central dogma of biology by discussing the most important molecules in cells (DNA, RNA and protein) and how their synthesis (DNA replication, transcription, RNA processing and translation) is regulated. Incorporated into the discussion is how recombinant DNA techniques are used to discover and dissect cellular processes, how to design and interpret experiments, and understanding the limits of experiments to draw conclusions.
MCDB 4990 - Honors Thesis
Primary Instructor
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Spring 2024
Involves the preparation and defense of an honors thesis, based on faculty-supervised original research, including final phases of the research project. Recommended prerequisites: MCDB 4840 or MCDB 4980 or comparable research experience, and minimum GPA of 3.3 and approval by the MCDB Honors Committee.
MCDB 6000 - Introduction to Laboratory Methods
Primary Instructor
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Spring 2020 / Fall 2020 / Spring 2021 / Fall 2021 / Spring 2022 / Fall 2023 / Spring 2024
Introduces methodology and techniques used in biological research. Designed as a tutorial between a few students and one faculty member. Students are expected to read original research papers, discuss findings, and to plan and execute experiments in selected areas. May be repeated up to 15 total credit hours.
