Dr. Alderete's research has contributed to our understanding of how air pollutants contribute to obesity and type 2 diabetes. Her work includes some of the first investigations to show that exposure to near-roadway and ambient air pollution contributes to obesity and the pathophysiology of type 2 diabetes in youth. While the mechanisms underlying these associations remain uncertain, Dr. Alderete's recent work has shown that exposure to near-roadway air pollution was associated with the relative abundance of specific gut bacteria that were also correlated with fasting glucose levels, including Bacteroidaceae and Coriobacteriaceae. Results from this study provide the first evidence that exposure to air pollutants may impact human health via alterations in the gut microbiota. Collectively, Dr. Alderete's current research aims to test the hypothesis that the microbiome plays an intimate role at the interface between human health and the environment.
IPHY 2800 - Introduction to Statistics
Spring 2019 / Spring 2020
Examines the application of statistics to research relevant to integrative physiology. Includes instruction and hands-on experience with related computer programs and interpretation of the results of their use. Recommended prerequisite: MATH 1300.
IPHY 3280 - Intro to Data Science and Biostatistics
Builds a foundation for modern data analysis and experimental design in the context of human physiology, health and disease. An intuitive understanding of probability, statistical methods, test outcomes and data relationships are emphasized over rigorous mathematical proofs. Foundational analytical skills using R and R Studio are developed using real and simulated data.