The Arnoult lab focuses on genome stability, DNA repair and telomere biology. We study the different types of pathways that cells use to repair DNA double strand breaks, and how telomeres escape these repair mechanisms. We are particularly interested in the mechanisms that control repair pathway selection during the different phases of the cell cycle, in link with cancer and aging.
MCDB 3135 - Molecular Cell Biology I
Fall 2019 / Fall 2020
Examines the central dogma of biology by discussing the most important molecules in cells (DNA, RNA and protein) and how their synthesis (DNA replication, transcription, RNA processing and translation) is regulated. Incorporated into the discussion is how recombinant DNA techniques are used to discover and dissect cellular processes, how to design and interpret experiments, and understanding the limits of experiments to draw conclusions.
MCDB 6000 - Introduction to Laboratory Methods
Spring 2020 / Fall 2020 / Spring 2021
Introduces methodology and techniques used in biological research. Designed as a tutorial between a few students and one faculty member. Students are expected to read original research papers, discuss findings, and to plan and execute experiments in selected areas. May be repeated up to 15 total credit hours.