Neurobiology of Aging

Overview

publication venue for

• Brain reserve in midlife is associated with executive function changes across 12 years 2024
• The shared genetic architecture of modifiable risk for Alzheimer's disease: a genomic structural equation modelling study 2022
• Paradoxical cognitive trajectories in men from earlier to later adulthood 2022
• Postoperative cognitive dysfunction is made persistent with morphine treatment in aged rats 2021
• APOE effects on cognition from childhood to adolescence 2019
Genetic risk for coronary heart disease alters the influence of Alzheimer's genetic risk on mild cognitive impairment 2019
Pupillary dilation responses as a midlife indicator of risk for Alzheimer's disease: association with Alzheimer's disease polygenic risk 2019
Mycobacterium vaccae immunization protects aged rats from surgery-elicited neuroinflammation and cognitive dysfunction 2018
High-fat diet and aging interact to produce neuroinflammation and impair hippocampal- and amygdalar-dependent memory 2017
Diminished circadian rhythms in hippocampal microglia may contribute to age-related neuroinflammatory sensitization 2016
Greater glucocorticoid receptor activation in hippocampus of aged rats sensitizes microglia 2015
Identifying A beta-specific pathogenic mechanisms using a nematode model of Alzheimer's disease 2015
The LDLR locus in alzheimer's disease: A family-based study and meta-analysis of case-control data 2007
Proteomic identification of proteins specifically oxidized in Caenorhabditis elegans expressing human Aβ(1-42):: Implications for Alzheimer's disease 2006
Peripheral infection and aging interact to impair hippocampal memory consolidation 2006
mRNA up-regulation of MHC II and pivotal pro-inflammatory genes in normal brain aging 2006
The beta amyloid peptide can function as a modular aggregation domain 2004
Gene expression analysis in a transgenic Caenorhabditis elegans Alzheimer's disease model 2003
Oxidative stress precedes fibrillar deposition of Alzheimer's disease amyloid β-peptide (1-42) in a transgenic Caenorhabditis elegans model 2003
Teaching old rats new tricks: age-related impairments in olfactory reversal learning. 2002
Visualization of fibrillar amyloid deposits in living, transgenic Caenorhabditis elegans animals using the sensitive amyloid dye, X-34 2001
Model systems for studying general aging processes - Introduction 1999
The spe-10 mutant has longer life and increased stress resistance 1999
In vitro and in vivo oxidative stress associated with Alzheimer's amyloid β-peptide (1-42) 1999
EXERCISE DOES NOT MODIFY SPATIAL MEMORY, BRAIN AUTOIMMUNITY, OR ANTIBODY-RESPONSE IN AGED F344 RATS 1991
... more

Research

keywords

• 1103 Clinical Sciences, 1109 Neurosciences