The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin disease
Journal Article
Overview
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Animals
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Animals, Inbred Strains - Mice, Inbred C3H
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Animals, Inbred Strains - Mice, Inbred C57BL
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Biochemical Phenomena - Base Sequence
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Carrier Proteins - Cation Transport Proteins
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Cells - Macrophages
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Cells, Cultured
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Connective Tissue Cells - Macrophages
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DNA Mutational Analysis
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Elements - Iron
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Genes - Genes, Dominant
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Genetic Structures - Base Sequence
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Humans
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Immune System - Macrophages
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Inheritance Patterns - Genes, Dominant
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Iron Metabolism Disorders
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Membrane Proteins - Cation Transport Proteins
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Metals - Iron
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Mice
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Mice - Mice, Inbred C3H
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Mice - Mice, Inbred C57BL
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Mice, Mutant Strains
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Molecular Sequence Data - Base Sequence
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Mononuclear Phagocyte System - Macrophages
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Mutation
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Myeloid Cells - Macrophages
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Protein Transport
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Transition Elements - Iron
Full Author List
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Zohn IE; De Domenico I; Pollock A; Ward DM; Goodman JF; Liang X; Sanchez AJ; Niswander L; Kaplan J
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