Occult regions of suppressed coherence in ultrasonic liver images Conference Proceeding uri icon



  • Lag-one coherence (LOC) estimates local levels of acoustic noise by measuring the spatial coherence between backscattered echo signals received by neighboring pairs of transducer elements. LOC can be directly related to signal to noise ratio (SNR) and contrast to noise ratio (CNR). We have acquired B-mode images and matched pixelwise LOC estimates in the livers of 10 healthy volunteers using a C5-2v probe on a Verasonics Vantage system and in Fullwave simulations with six abdominal walls over uniform speckle. We present evidence of temporally stable regions of suppressed LOC beneath the abdominal wall which recover to a stable asymptotic value at depth. Fullwave simulation results suggest that reverberation determines the initial amount of coherence suppression and aberration determines the asymptotic LOC value. The in vivo LOC values beneath the abdominal wall range from roughly 0.4 to 0.85, corresponding to SNRs of −3.5 dB to 15 dB, and the length of coherence suppression ranges from 0.5cm to 2.5 cm. These regions are occult; they present as temporally stable uniform liver on B-mode images. This is significant because clinicians will not be aware that lesions may be much more difficult to detect in this region, potentially leading to missed diagnoses.

publication date

  • October 1, 2020

has restriction

  • closed

Date in CU Experts

  • January 8, 2021 12:24 PM

Full Author List

  • Offerdahl K; Huber M; Long J; Long W; Bottenus N; Trahey G

author count

  • 6

Other Profiles

International Standard Serial Number (ISSN)

  • 0001-4966

Electronic International Standard Serial Number (EISSN)

  • 1520-8524

Additional Document Info

start page

  • 2487

end page

  • 2487


  • 148


  • 4_Supplement