The subdiffusive targeting problem. Journal Article uri icon

Overview

abstract

  • Recent experiments in living cells have observed subdiffusive motion, where the mean squared displacement of a molecule grows sublinearly with time as [x (2)] approximately t(alpha). Motivated by these experiments, we develop a theory for subdiffusion-limited bimolecular enzyme kinetics. As in normal diffusion, the statistics of the reaction times depend on the ratio between the distance to the target and the reaction rate in a scale invariant manner. Contrary to some studies, we find no critical value of alpha and therefore no evidence to suggest that it has been a target of evolutionary optimization.

publication date

  • April 1, 2008

Full Author List

  • Eaves JD; Reichman DR

Other Profiles

Additional Document Info

start page

  • 4283

end page

  • 4289

volume

  • 112

issue

  • 14