tudor, a gene required for assembly of the germ plasm in Drosophila melanogaster. Journal Article uri icon

Overview

abstract

  • Developmental analysis of a newly isolated maternal effect grandchildless mutant, tudor (tud), in Drosophila melanogaster indicates that tud+ activity is required during oogenesis for the determination and/or formation of primordial germ cells (pole cells) and for normal embryonic abdominal segmentation. Regardless of their genotype, progeny of females homozygous for strong alleles (tud1 and tud3) never form pole cells, apparently lack polar granules in the germ plasm, and approximately 40% of them die during late embryogenesis exhibiting severe abdominal segmentation pattern defects. Females carrying weak allele, tud4, produce progeny with some functional pole cells and form polar granules approximately one-third the size of those observed in wild-type oocytes and embryos. No segmentation abnormalities are observed in the inviable embryos derived from tud4/tud4 females.

publication date

  • November 1, 1985

Date in CU Experts

  • October 28, 2013 10:10 AM

Full Author List

  • Boswell RE; Mahowald AP

author count

  • 2

citation count

  • 149

published in

Other Profiles

International Standard Serial Number (ISSN)

  • 0092-8674

Electronic International Standard Serial Number (EISSN)

  • 1097-4172

Additional Document Info

start page

  • 97

end page

  • 104

volume

  • 43

issue

  • 1