Dr. Tay's research is focused on the use and development of computational tools to analyze microscope images of biological cells. He has developed a number of toolboxes to identify cells in time-lapse microscope images, identifying and tracking cell division events, tracking subcellular protein complexes, as well as analyzing and visualizing the resulting complex datasets. His current research focuses on studying sub-cellular processes in single cells, including studying photodamage and repair in cyanobacteria, and phage infection of bacteria using machine-learning. Previously, he worked on projects to study the role of zinc on mammalian cell division, quantifying the structures responsible for cellular movement, how the shape of the nucleus affects the speed of recruitment of repair proteins, and studying the role of mechanical forces between neighboring cells on the regulation of photosynthesis.
BCHM 4312 - Quantitative Optical Imaging
Primary Instructor
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Fall 2020 / Fall 2021 / Fall 2023
Explores the fundamentals of optical imaging in biology, especially molecular and cellular biology. Covered topics include an introduction to optics and microscopes, fluorescence microscopy and image analysis, and biological applications. MATLAB will be taught at the beginning of the course and used throughout for image processing. Prior experience with MATLAB (or Python) is highly recommended but not required. Same as MCDB 4312, MCDB 5312 and BCHM 5312.
BCHM 5312 - Quantitative Optical Imaging
Primary Instructor
-
Fall 2020 / Fall 2021 / Fall 2022 / Fall 2023
Explores the fundamentals of optical imaging in biology, especially molecular and cellular biology. Covered topics include an introduction to optics and microscopes, fluorescence microscopy and image analysis, and biological applications. MATLAB will be taught at the beginning of the course and used throughout for image processing. Prior experience with MATLAB (or Python) is highly recommended but not required. Same as MCDB 5312, MCDB 4312 and BCHM 4312.
MCDB 4100 - Special Topics
Primary Instructor
-
Fall 2021
May be repeated up to 6 total credit hours. Recommended prerequisites: MCDB 3135 and MCDB 3145 (minimum grade C-).
MCDB 4312 - Quantitative Optical Imaging
Primary Instructor
-
Fall 2020 / Fall 2021 / Fall 2022 / Fall 2023
Explores the fundamentals of optical imaging in biology, especially molecular and cellular biology. Covered topics include an introduction to optics and microscopes, fluorescence microscopy and image analysis, and biological applications. MATLAB will be taught at the beginning of the course and used throughout for image processing. Prior experience with MATLAB (or Python) is highly recommended but not required. Same as BCHM 4312, MCDB 5312 and BCHM 5312.
MCDB 5312 - Quantitative Optical Imaging
Primary Instructor
-
Fall 2020 / Fall 2021 / Fall 2022 / Fall 2023
Explores the fundamentals of optical imaging in biology, especially molecular and cellular biology. Covered topics include an introduction to optics and microscopes, fluorescence microscopy and image analysis, and biological applications. MATLAB will be taught at the beginning of the course and used throughout for image processing. Prior experience with MATLAB (or Python) is highly recommended but not required. Same as BCHM 5312, MCDB 4312 and BCHM 4312.
MCDB 6440 - Special Topics in MCD Biology
Primary Instructor
-
Fall 2021 / Fall 2024
Acquaints students with various topics not normally covered in the curriculum. Offered intermittently or upon student demand, and often presented by visiting professors. May be repeated up to 6 total credit hours.
