• Contact Info

Arnold, Mathew R

Instructor

Positions

Research Areas research areas

Research

research overview

  • My primary areas of research interest include neural mechanisms underlying anxiety and affective disorders, risk factors for the development and persistence of these disorders, such as inflammation, genetic predisposition, microbiome makeup and development of novel strategies for both the prevention and treatment of these disorders. A major focus of my work is on the role of the serotonin system in the production and maintenance of psychopathology. Specifically, I have quantified the expression changes in key serotonin system related genes in a variety of experimental paradigms including treatment and prevention a non-pathogenic, saprophytic bacteria with anti-inflammatory and immunoregulatory properties, anxiogenic drugs, knock-out models, circadian disruption, as well as a rat model of autism. Currently, I am focused on quantifying the involvement of the microbiome on changes of these genes in addition to quantifying how changes to the microbiome influences genetic changes.

keywords

  • Serotonin, psychopathology, microbiome, anxiety, depression, therapy

Teaching

courses taught

  • BAIM 4065 - Leadership in a Digital Age
    Primary Instructor - Summer 2021
    In the digital age, leaders have to orchestrate radical redesign of everything from their internal processes to their business model on an ongoing basis. This requires leaders to adopt new approaches to leadership and new behaviors. This course provides students with the skills required in identifying business opportunities, finding appropriate information related technologies and leading innovation efforts to success. Formerly MGMT 4065.
  • BCOR 1025 - Statistical Analysis in Business
    Primary Instructor - Spring 2020 / Spring 2021 / Spring 2022 / Summer 2022 / Spring 2023 / Summer 2023 / Spring 2024
    Covers sampling concepts, graphical and numerical data summaries, basic probability theory, discrete and continuous probability models, sampling distributions, hypothesis testing, correlation and both simple and multiple regression analysis. Students learn decision making and solving business problems by using data. Uses statistical features of Excel. Course requirements: laptop with Excel 2013 or newer; clickers. Credit not granted for this course and BCOR 1020.
  • BCOR 2202 - Principles of Organizational Behavior
    Primary Instructor - Spring 2024
    Focuses on the fundamentals of management. Students will learn the basic concepts and best practices in the behavioral sciences that can improve their abilities to lead and manage in organizations. Frameworks for individual, team, and organizational behavior are presented and discussed. Topics include personality traits, culture, decision making, teams, planning, motivation, leadership, well-being and human resources. A group project provides practice in teamwork and in applying the frameworks in practice. Credit not granted for this course and BCOR 2300, BCOR 2001
  • BCOR 2205 - Introduction to Information Management and Analytics
    Primary Instructor - Fall 2020 / Spring 2021 / Fall 2021 / Fall 2022 / Fall 2023
    Focuses on the fundamentals of managing information in a data driven business environment. Students will learn the basic concepts and best practices in Information Management that can improve their abilities to lead and manage in organizations. The class teaches cutting-edge tools and approaches to the analysis of data, including "big data," for effective decision-making.It creates data connoisseurs through hands-on exposure to supervised machine learning. Application areas covered include human resources, marketing, finance, and supply chain. At the end of class, all students should be able to formulate common business problems in terms addressable through machine learning, and use automated machine learning tools to conduct the analysis and present deep insights to business leaders. Course requirements: clickers. Credit not granted for this course and BCOR 2500.
  • BUSM 3010 - Managing Innovation I
    Primary Instructor - Spring 2021 / Fall 2021 / Spring 2022 / Fall 2022 / Spring 2023
    Examines structures that support organizational innovation and change. Focuses on effective teamwork and tools needed during new product development to improve success. Degree credit not granted for this course and BUSM 3001.
  • IPHY 3415 - Human Anatomy Laboratory
    Primary Instructor - Spring 2018 / Fall 2018
    Introduces structures of the human anatomical systems using human cadavers and animal tissue. This laboratory is meant to complement IPHY 3410. Same as IPHY 3417.
  • NRSC 2100 - Introduction to Neuroscience
    Teaching Assistant - Spring 2019
    Provides an introduction to fundamental concepts in neuroscience. The goal of this first course is to provide a strong foundation in neurobiology-cell biology, physiology of the neuronal membrane, interneuronal communication, neurotransmission, gross anatomy, and how the brain develops. Students will also learn principles of sensory systems functions. Recitation will reinforce lecture concepts through discussion of current research.

Background

Other Profiles