selected publications
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chapter
- The EGFR/ERBB Receptor Family. 107-164. 2015
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conference proceeding
- Trackable genome engineering with single nucleotide resolution. ACS National Meeting Book of Abstracts. 2016
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journal article
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Predicting Drug Resistance Using Deep Mutational Scanning.
Molecules.
2020
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Genomic Deoxyxylulose Phosphate Reductoisomerase (DXR) Mutations Conferring Resistance to the Antimalarial Drug Fosmidomycin in E. coli.
ACS Synthetic Biology.
2824-2832.
2018
- Genomic Deoxyxylulose Phosphate Reductoisomerase (DXR) Mutations Confering Resistance to the Antimalarial Drug Fosmidomycin in E. coli. ACS Synthetic Biology. 2018
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SILAC identifies LAD1 as a filamin-binding regulator of actin dynamics in response to EGF and a marker of aggressive breast tumors.
Science Signaling.
2018
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Dynamic Management of Codon Compression for Saturation Mutagenesis.
Methods in Molecular Biology.
171-189.
2018
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Refactoring the Genetic Code for Increased Evolvability.
mBio.
2017
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Quantitative Tracking of Combinatorially Engineered Populations with Multiplexed Binary Assemblies.
ACS Synthetic Biology.
619-627.
2017
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Genome-wide mapping of mutations at single-nucleotide resolution for protein, metabolic and genome engineering.
Nature Biotechnology.
48-55.
2017
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The Resistome: A Comprehensive Database of Escherichia coli Resistance Phenotypes.
ACS Synthetic Biology.
1566-1577.
2016
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Interfering with the Dimerization of the ErbB Receptors by Transmembrane Domain-Derived Peptides Inhibits Tumorigenic Growth in Vitro and in Vivo.
Biochemistry.
5520-5530.
2016
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A Web Interface for Codon Compression.
ACS Synthetic Biology.
1021-1023.
2016
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Bacterial Recombineering: Genome Engineering via Phage-Based Homologous Recombination.
ACS Synthetic Biology.
1176-1185.
2015
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Multiplexed tracking of combinatorial genomic mutations in engineered cell populations.
Nature Biotechnology.
631-+.
2015
-
Codon Compression Algorithms for Saturation Mutagenesis.
ACS Synthetic Biology.
604-614.
2015
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Evolutionary Genomics..
Evolutionary Bioinformatics.
53-55.
2015
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Deubiquitination of EGFR by Cezanne-1 contributes to cancer progression.
Oncogene.
4599-4608.
2012
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The ERBB network: at last, cancer therapy meets systems biology.
Nature Reviews Cancer.
553-563.
2012
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EGR1 and the ERK-ERF axis drive mammary cell migration in response to EGF.
The FASEB Journal.
1582-1592.
2012
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Kinase-mediated quasi-dimers of EGFR.
The FASEB Journal.
4744-4755.
2010
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EGFRvIV: a previously uncharacterized oncogenic mutant reveals a kinase autoinhibitory mechanism.
Oncogene.
5850-5860.
2010
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Oncogenic mutant forms of EGFR: Lessons in signal transduction and targets for cancer therapy.
FEBS Letters.
2699-2706.
2010
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Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling.
Oncogene.
6968-6978.
2007
-
Predicting Drug Resistance Using Deep Mutational Scanning.
Molecules.
2020