Negative Supercoiling Creates Single-Stranded Patches of DNA That Are Substrates for AID-Mediated Mutagenesis
Journal Article
Overview
publication date
- February 1, 2012
has subject area
- Animals
- Anions - Sulfites
- Biochemical Phenomena - Deamination
- Biochemical Phenomena - Immunoglobulin Variable Region
- Biochemical Phenomena - Transcription, Genetic
- Blood Proteins - Immunoglobulin Variable Region
- Blood Proteins - Immunoglobulin Variable Region
- Cells - B-Lymphocytes
- Cells - B-Lymphocytes
- Cellular Structures - Cell Nucleus
- Cytidine Deaminase
- DNA
- DNA - DNA, Single-Stranded
- Endonucleases - Ribonuclease H
- Gammaproteobacteria - Escherichia coli
- Gene Expression - Transcription, Genetic
- Gene Rearrangement - Immunoglobulin Class Switching
- Genetic Structures - DNA, Single-Stranded
- Globulins - Immunoglobulin Variable Region
- Globulins - Immunoglobulin Variable Region
- Gram-Negative Facultatively Anaerobic Rods - Escherichia coli
- Hemic and Immune Systems - B-Lymphocytes
- Humans
- Immune System - B-Lymphocytes
- Immune System - B-Lymphocytes
- Immunogenetic Phenomena - Immunoglobulin Class Switching
- Immunogenetic Phenomena - Somatic Hypermutation, Immunoglobulin
- Immunoproteins - Immunoglobulin Variable Region
- Immunoproteins - Immunoglobulin Variable Region
- Inorganic Chemicals - Sulfites
- Metabolism - Deamination
- Mice
- Molecular Conformation - DNA, Single-Stranded
- Mutagenesis - Somatic Hypermutation, Immunoglobulin
- Nucleic Acids, Nucleotides, and Nucleosides - Cytidine
- Organelles - Cell Nucleus
- Organic Chemistry Phenomena - Deamination
- Peptide Fragments - Immunoglobulin Variable Region
- Pyrimidines - Cytidine
- Ribonucleases - Ribonuclease H
- Ribonucleosides - Cytidine
- Substrate Specificity
has restriction
- gold
Date in CU Experts
- September 9, 2013 10:05 AM
Full Author List
- Parsa J-Y; Ramachandran S; Zaheen A; Nepal RM; Kapelnikov A; Belcheva A; Berru M; Ronai D; Martin A
author count
- 9
citation count
- 40
published in
- PLoS Genetics Journal
Other Profiles
International Standard Serial Number (ISSN)
- 1553-7390
Digital Object Identifier (DOI)
Additional Document Info
volume
- 8
issue
- 2
number
- ARTN e1002518