Effects of naltrexone on alcohol sensitivity and genetic moderators of medication response - A double-blind placebo-controlled study
Journal Article
Overview
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Adult
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Alcohol Drinking
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Behavior, Addictive
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Biological Science Disciplines - Pharmacogenetics
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Breath Tests
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Central Nervous System Agents - Narcotic Antagonists
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Chemically-Induced Disorders - Alcoholism
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Emotions
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Environment and Public Health - Double-Blind Method
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Environment and Public Health - Prospective Studies
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Ethanol
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Female
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Genetic Variation
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Genetics - Pharmacogenetics
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Genotype
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Health Care Evaluation Mechanisms - Double-Blind Method
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Health Care Evaluation Mechanisms - Prospective Studies
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Health Occupations - Pharmacogenetics
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Heterocyclic Compounds, 4 or More Rings - Naltrexone
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Heterocyclic Compounds, Bridged-Ring - Naltrexone
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Humans
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Investigative Techniques - Double-Blind Method
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Investigative Techniques - Prospective Studies
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Male
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Mental Disorders - Alcoholism
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Methods - Double-Blind Method
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Opiate Alkaloids - Naltrexone
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Pharmaceutical Preparations - Placebos
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Physiological Effects of Drugs - Narcotic Antagonists
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Polycyclic Compounds - Naltrexone
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Polymorphism, Single Nucleotide
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Receptors, G-Protein-Coupled - Receptors, Opioid, mu
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Receptors, Neurotransmitter - Receptors, Opioid, mu
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Receptors, Peptide - Receptors, Opioid, mu
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Reward
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Sensory System Agents - Narcotic Antagonists
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Therapeutics - Placebos
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