Stm1 modulates translation after 80S formation in Saccharomyces cerevisiae Journal Article uri icon

Overview

abstract

  • The control of translation is a critical aspect of gene regulation. It is often inversely related to mRNA degradation and is typically controlled during initiation. The Stm1 protein in Saccharomyces cerevisiae has been shown to interact with ribosomes, affect the interaction of eEF3 with ribosomes, and promote the decapping of a subclass of mRNAs. We demonstrate that in vitro Stm1 inhibits translation after formation of an 80S complex. This suggests that Stm1 modulates translation and mRNA decapping by controlling translation elongation.

publication date

  • May 1, 2011

Date in CU Experts

  • February 20, 2014 11:03 AM

Full Author List

  • Balagopal V; Parker R

author count

  • 2

published in

  • RNA  Journal

Other Profiles

International Standard Serial Number (ISSN)

  • 1355-8382

Electronic International Standard Serial Number (EISSN)

  • 1469-9001

Additional Document Info

start page

  • 835

end page

  • 842

volume

  • 17

issue

  • 5