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Parker, Roy Distinguished Professor, Cech-Leinwand Endowed Chair of Biochemistry, and Howard Hughes Medical Institute Investigator

Positions

Research Areas research areas

Research

research overview

  • My current major area of work is to understand the molecular mechanisms that control eukaryotic mRNAs in the cytoplasm with a specifc focus on the control of translation, mRNA localization and stability. We employ a variety of experimental models including bakers yeast, mammalian cells in culture, Drosophila and mice. Current work focuses on trying to understand how RNP granules, such as P-bodies and stress granules assemble, their roles in regulating mRNA function in cells, and how perturbations of these assemblies can cause human disease. This work also includes studies of related mRNP granules in neurons and regenerating muscle, both in normal conditions and during pathologies.

keywords

  • mRNA turnover, translation, P-bodies, mRNA degradation, Eukaryotic cells

Publications

selected publications

Teaching

courses taught

  • CHEM 1041 Biotechnology and Society (Spring 2019)
  • CHEM 6901 Research in Chemistry (Spring 2019)
  • CHEM 8991 Doctoral Dissertation (Spring 2019)
  • MCDB 8990 Doctoral Dissertation (Spring 2019)
  • CHEM 6901 Research in Chemistry (Fall 2018)
  • CHEM 8991 Doctoral Dissertation (Fall 2018)
  • CHEM 6901 Research in Chemistry (Summer 2018)
  • CHEM 8991 Doctoral Dissertation (Summer 2018)
  • CHEM 4761 Biochemistry Laboratory (Spring 2018)
  • CHEM 6901 Research in Chemistry (Spring 2018)
  • CHEM 8991 Doctoral Dissertation (Spring 2018)
  • MCDB 8990 Doctoral Dissertation (Spring 2018)

Background

awards and honors

International Activities

Other Profiles