ELT-1, a GATA-like transcription factor, is required for epidermal cell fates in Caenorhabditis elegans embryos. Journal Article uri icon

Overview

abstract

  • Epidermal cells are generated during Caenorhabditis elegans embryogenesis by several distinct lineage patterns. These patterns are controlled by maternal genes that determine the identities of early embryonic blastomeres. We show that the embryonically expressed gene elt-1, which was shown previously to encode a GATA-like transcription factor, is required for the production of epidermal cells by each of these lineages. Depending on their lineage history, cells that become epidermal in wild-type embryos become either neurons or muscle cells in elt-1 mutant embryos. The ELT-1 protein is expressed in epidermal cells and in their precursors. We propose that elt-1 functions at an early step in the specification of epidermal cell fates.

publication date

  • July 1, 1997

Date in CU Experts

  • April 24, 2014 12:22 PM

Full Author List

  • Page BD; Zhang W; Steward K; Blumenthal T; Priess JR

author count

  • 5

Other Profiles

International Standard Serial Number (ISSN)

  • 0890-9369

Electronic International Standard Serial Number (EISSN)

  • 1549-5477

Additional Document Info

start page

  • 1651

end page

  • 1661

volume

  • 11

issue

  • 13