research overview
- Research in the RDI Lab centers on using computational tools and approaches to study interfacial phenomena, whether that be the interface between: (1) an antibody and highly-mutable pathogen like HIV to enable the design of universal vaccines, (2) a small-molecule drug and cellular membrane to aid in creating novel therapeutics for treating neurological diseases like Alzheimer's, (3) a polymer and metal oxide surface to enable advances in plastics upcycling, or (4) an electrolyte and cathode material towards the development of next-generation Li-ion batteries. We employ tools spanning the atomistic to population level, including mathematical evolutionary modeling, physics-based simulations, bioinformatics, and machine learning. Our work is highly interdisciplinary, focused at the crossroads of physics, engineering and immunology, and we work in close synergy with experimentalists to inform, validate, and test our computational predictions.
