selected publications
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journal article
- Two Classes of Myosin Inhibitors, Para-nitroblebbistatin and Mavacamten, Stabilize β-Cardiac Myosin in Different Structural and Functional States. Journal of Molecular Biology. 2021
- Contractility parameters of human β-cardiac myosin with the hypertrophic cardiomyopathy mutation R403Q show loss of motor function. Science Advances. 2015
- The Python Project: A Unique Model for Extending Research Opportunities to Undergraduate Students. CBE : Life Sciences Education. 698-710. 2014
- The Hypertrophic Cardiomyopathy Myosin Mutation R453C Alters ATP Binding and Hydrolysis of Human Cardiac β- Myosin*. Journal of Biological Chemistry. 5158-5167. 2014
- Hydrogels preserve native phenotypes of valvular fibroblasts through an elasticity-regulated PI3K/AKT pathway. Proceedings of the National Academy of Sciences of USA. 19336-19341. 2013
- Use of integrin-linked kinase to extend function of encapsulated pancreatic tissue. Biomedical Materials. 2010
- A Mediator of Rho-dependent Invasion Moonlights as a Methionine Salvage Enzyme. Molecular and Cellular Proteomics. 2308-2320. 2009
- Immunological priming potentiates non-viral anti-inflammatory gene therapy treatment of neuropathic pain. Gene Therapy (Basingstoke). 1210-1222. 2009
- Immunogenicity of intrathecal plasmid gene delivery: cytokine release and effects on transgene expression. Journal of Gene Medicine. 782-790. 2009
- Intrathecal Injection of Naked Plasmid DNA Provides Long-term Expression of Secreted Proteins. Molecular Therapy. 88-94. 2009
- A randomized library approach to identifying functional lox site domains for the Cre recombinase. Nucleic Acids Research. 5464-5473. 2007
- Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats. Brain, Behavior, and Immunity. 686-698. 2007
- Student award winner in the undergraduate degree category for the society for biomaterials, 32nd Annual Meeting, Chicago, Illinois, April 17-20, 2007. Journal of Biomedical Materials Research Part A. 259-268. 2007
- Repeated intrathecal injections of plasmid DNA encoding interleukin-10 produce prolonged reversal of neuropathic pain. Pain. 294-308. 2006
- Functional proteomics identifies protein-tyrosine phosphatase 1B as a target of RhoA signaling. Molecular and Cellular Proteomics. 1359-1367. 2006
- ITRs Necessary for IL-10 Encoding Naked Plasmid Induced Reversal of Chronic Pain State in Rat. Molecular Therapy. S100-S100. 2006
- In Vivo Over-Expression of Fractalkine, a Putative Neuron-to-Glia Signal, To Characterize Underlying Mechanisms of Neuropathic Pain. Molecular Therapy. S100-S100. 2006
- Plasmid DNA Encoding the Anti-Inflammatory Cytokine Gene, Interleukin-10 (IL-10) for Chronic Pain Control: Taking Advantage of Nuclear Scaffold/Matrix Attachment Regions. Molecular Therapy. S99-S99. 2006
- Intrathecal polymer-based interleukin-10*gene delivery for neuropathic pain. Neuron Glia Biology. 293-308. 2006
- Controlling pathological pain by adenovirally driven spinal production of the anti-inflammatory cytokine, interleukin-10. European Journal of Neuroscience. 2136-2148. 2005
- Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10. Molecular Pain. 2005
- The Ku protein complex interacts with YY1, is up-regulated in human heart failure, and represses α myosin heavy-chain gene expression. Molecular and Cellular Biology. 8705-8715. 2004
- A role for proinflammatory cytokines and fractalkine in analgesia, tolerance, and subsequent pain facilitation induced by chronic intrathecal morphine. The Journal of Neuroscience. 7353-7365. 2004
- Spinal interleukin-10 (IL-10) gene therapy using viral and non-viral vectors controls inflammatory- and chronic constriction injury-induced pain states in rats. Molecular Therapy. S200-S201. 2004
- Rational promoter selection for gene transfer into cardiac cells. Journal of Molecular and Cellular Cardiology. 823-831. 2003
- Acute effects of desmin mutations on cytoskeletal and cellular integrity in cardiac myocytes. Cytoskeleton. 105-121. 2003
- A genetic screen identifies novel non-compatible IoxP sites. Nucleic Acids Research. 3067-3077. 2002
- Potential limitations of transcription terminators used as transgene insulators in adenoviral vectors. Gene Therapy (Basingstoke). 227-231. 2002
- Potential limitations of transcription terminators used as transgene insulators in adenoviral vectors.. Gene Therapy (Basingstoke). 227-231. 2002
- Overexpression of the plasma membrane calcium ATPase isoform 4b dose-dependently affects growth and survival of neonatal rat cardiomyocytes. Circulation. 137-137. 2001