Immunogenicity of intrathecal plasmid gene delivery: cytokine release and effects on transgene expression
Journal Article
Overview
publication date
- September 1, 2009
has subject area
- Animals
- Antigens, Surface - Toll-Like Receptor 9
- Biochemical Phenomena - CpG Islands
- Biological Factors - Cytokines
- Biological Therapy - Genetic Therapy
- Biomarkers - Toll-Like Receptor 9
- Cell Line
- DNA-Binding Proteins - Toll-Like Receptor 9
- Gene Expression
- Gene Transfer Techniques - Transfection
- Genetic Engineering - Genetic Therapy
- Genetic Structures - CpG Islands
- Genome Components - CpG Islands
- Humans
- Injections, Spinal
- Male
- Peptides - Cytokines
- Plasmids
- Proteins - Cytokines
- Rats
- Rats, Sprague-Dawley
- Recombination, Genetic - Transfection
- Toll-Like Receptors - Toll-Like Receptor 9
- Transgenes
Date in CU Experts
- September 6, 2013 4:09 AM
Full Author List
- Hughes TS; Langer SJ; Virtanen SI; Chavez RA; Watkins LR; Milligan ED; Leinwand LA
author count
- 7
citation count
- 13
published in
- Journal of Gene Medicine Journal
Other Profiles
International Standard Serial Number (ISSN)
- 1099-498X
Electronic International Standard Serial Number (EISSN)
- 1521-2254
Digital Object Identifier (DOI)
Additional Document Info
start page
- 782
end page
- 790
volume
- 11
issue
- 9