selected publications
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journal article
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Specificity of Phosphorylation Responses to Mitogen Activated Protein (MAP) Kinase Pathway Inhibitors in Melanoma Cells.
Molecular and Cellular Proteomics.
550-564.
2018
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Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications.
Cell Reports.
1173-1186.
2017
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A Synonymous Mutation Upstream of the Gene Encoding a Weak-Link Enzyme Causes an Ultrasensitive Response in Growth Rate.
Journal of Bacteriology.
2853-2863.
2016
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Identification of Mediator Kinase Substrates in Human Cells using Cortistatin A and Quantitative Phosphoproteomics.
Cell Reports.
436-450.
2016
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Mediator kinase inhibition further activates super-enhancer-associated genes in AML.
Nature.
273-+.
2015
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Architecture of the Human and Yeast General Transcription and DNA Repair Factor TFIIH.
Molecular Cell.
794-806.
2015
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Licensing of Yeast Centrosome Duplication Requires Phosphoregulation of Sfi1.
PLoS Genetics.
2014
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TRIM28 regulates RNA polymerase II promoter-proximal pausing and pause release.
Nature Structural and Molecular Biology.
876-883.
2014
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The Mediator complex and transcription regulation.
Critical Reviews in Biochemistry and Molecular Biology.
575-608.
2013
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FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2.
Genes and Development.
2690-2695.
2012
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Mediator and cohesin connect gene expression and chromatin architecture (vol 467, pg 430, 2010).
Nature.
247-247.
2011
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Molecular Architecture of the Human Mediator-RNA Polymerase II-TFIIF Assembly.
PLoS Biology.
2011
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Mediator and cohesin connect gene expression and chromatin architecture.
Nature.
430-435.
2010
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Activator-Mediator binding regulates Mediator-cofactor interactions.
Proceedings of the National Academy of Sciences of USA.
11283-11288.
2010
- CDK8 is a positive regulator of transcriptional elongation within the serum response network.. The FASEB Journal. 2010
- Mediator co-activator function is controlled by activator-induced structural shifts. The FASEB Journal. 2010
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CDK8 is a positive regulator of transcriptional elongation within the serum response network.
Nature Structural and Molecular Biology.
194-U9.
2010
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Sulfation of tibolone metabolites by human postmenopausal liver and small intestinal sulfotransferases (SULTs)..
Steroids.
343-351.
2006
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Human thyroid phenol sulfotransferase enzymes 1A1 and 1A3: activities in normal and diseased thyroid glands, and inhibition by thyroid hormones and phytoestrogens..
Journal of Clinical Endocrinology and Metabolism.
5597-5605.
2004
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Specificity of Phosphorylation Responses to Mitogen Activated Protein (MAP) Kinase Pathway Inhibitors in Melanoma Cells.
Molecular and Cellular Proteomics.
550-564.
2018