Chemistry and Biology Journal

Overview

publication venue for

• Metal Ion-Mediated Nucleobase Recognition by the ZTP Riboswitch 2015
• A Disconnect between High-Affinity Binding and Efficient Regulation by Antifolates and Purines in the Tetrahydrofolate Riboswitch 2014
• AAK1 Identified as an Inhibitor of Neuregulin-1/ErbB4-Dependent Neurotrophic Factor Signaling Using Integrative Chemical Genomics and Proteomics 2011
• Novel Ligands for a Purine Riboswitch Discovered by RNA-Ligand Docking 2011
• SNAP-Shots of Hydrogen Peroxide in Cells 2010
Toward the Rational Design of p53-Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant 2010
Membrane-Permeant Phosphoinositide Derivatives as Modulators of Growth Factor Signaling and Neurite Outgrowth 2009
Quantification of real-time Salmonella effector type III secretion kinetics reveals differential secretion rates for SopE2 and SptP 2008
Effects of photochemically activated alkylating agents of the FR900482 family on chromatin 2007
Riboswitches: Fold and function 2006
One, two, infinity: Genomes filled with aptamers 2002
Steric interference modification of the hammerhead ribozyme 2002
RNA aptamers as pathway-specific MAP kinase inhibitors 2000
Allosteric drugs: thinking outside the active-site box 2000
Probing the binding of Tb(III) and Eu(III) to the hammerhead ribozyme using luminescence spectroscopy 1999
Peptidyl-transferase ribozymes: trans reactions, structural characterization and ribosomal RNA-like features 1998
RNA aptamers to the peptidyl transferase inhibitor chloramphenicol 1997
Diverse mechanistic approaches to difficult chemical transformations: Microbial dehalogenation of chlorinated aromatic compounds 1997
Identification and localization of a stable sulfenic acid in peroxide-treated tetrachlorohydroquinone dehalogenase using electrospray mass spectrometry 1996
LETS GET SPECIFIC - THE RELATIONSHIP BETWEEN SPECIFICITY AND AFFINITY 1995
... more

Research

keywords

• 0304 Medicinal and Biomolecular Chemistry, 0305 Organic Chemistry, 0601 Biochemistry and Cell Biology