Allosteric drugs: thinking outside the active-site box. Journal Article uri icon



  • Recently, a class of small molecules that thermally stabilize the tumor suppressor p53 was selected from a small-molecule library. This, and other recent work, demonstrates the feasibility of taking a lead from nature and selecting new classes of drugs that function by allosteric mechanisms.

publication date

  • May 1, 2000

has subject area

has restriction

  • hybrid

Date in CU Experts

  • September 4, 2015 2:01 AM

Full Author List

  • DeDecker BS

author count

  • 1

Other Profiles

International Standard Serial Number (ISSN)

  • 1074-5521

Additional Document Info

start page

  • R103

end page

  • R107


  • 7


  • 5