The EMBO Journal Journal

Overview

publication venue for

• Mechanisms and physiological function of daily haemoglobin oxidation rhythms in red blood cells 2023
• Nucleic acid-protein condensates in innate immune signaling 2023
• RNA is required for the integrity of multiple nuclear and cytoplasmic membrane-less RNP granules 2022
• Reorganization of inter-chromosomal interactions in the 2q37-deletion syndrome 2018
• High-throughput identification of RNA nuclear enrichment sequences 2018
• Expanding our scientific horizons: utilization of unique model organisms in biological research 2017
• TDP-1, the Caenorhabditis elegans ortholog of TDP-43, limits the accumulation of double-stranded RNA 2014
• Molecular functions of the TLE tetramerization domain in Wnt target gene repression 2014
• RNA polymerase II acts as an RNA-dependent RNA polymerase to extend and destabilize a non-coding RNA 2013
• A DR4:tBID axis drives the p53 apoptotic response by promoting oligomerization of poised BAX 2012
• POT1-TPP1 enhances telomerase processivity by slowing primer dissociation and aiding translocation 2010
• Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3 2008
• Dual mechanisms specify Doa4-mediated deubiquitination at multivesicular bodies 2007
• Structural and functional insights into the human Upf1 helicase core 2007
• Multiple mechanisms are involved in regulating the expression of the developmental timing regulator lin-28 in Caenorhabditis elegans 2006
• An 8 nt RNA triggers a rate-limiting shift of RNA polymerase II complexes into elongation 2006
• A structural model for monastrol inhibition of dimeric kinesin Eg5 2006
• Drosophila sex-lethal protein mediates polyadenylation switching in the female germline 2006
• Protein activation of a ribozyme: the role of bacterial RNase P protein 2005
• The yeast EDC1 mRNA undergoes deadenylation-independent decapping stimulated by Not2p, Not4p, and Not5p 2005
• Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha 2005
• Nucleosomes containing the histone variant H2A.Bbd organize only 118 base pairs of DNA 2004
• Modulation of kinesin binding by the C-termini of tubulin 2004
• Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions 2004
• Modulation of KSR activity in Caenorhabditis elegans by Zn ions, PAR-1 kinase and PP2A phosphatase 2004
• CRN-1, a Caenorhabditis elegans FEN-1 homologue, cooperates with CPS-6/EndoG to promote apoptotic DNA degradation 2003
• Drosophila polypyrimidine-tract binding protein (PTB) functions specifically in the male germline 2003
• Importin α-regulated nucleation of microtubules by TPX2 2003
• Nucleotide-induced conformations in the neck region of dimeric kinesin 2003
• Microscopic evidence for a minus-end-directed power stroke in the kinesin motor ncd 2002
• Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex inSaccharomyces cerevisiae 2002
• Structure of a fast kinesin: implications for ATPase mechanism and interactions with microtubules 2001
• Escherichia coli DbpA is an RNA helicase that requires hairpin 92 of 23S rRNA 2001
• Structure of the yeast nucleosome core particle reveals fundamental changes in internucleosome interactions 2001
• Analysis of heterodimer formation by Xklp3A/B, a newly cloned kinesin-II from Xenopus laevis 2001
• A novel assembly mechanism for the DNA polymerase III holoenzyme DnaX complex: association of deltadelta' with DnaX(4) forms DnaX(3)deltadelta'. 2000
• The Puf3 protein is a transcript-specific regulator of mRNA degradation in yeast 2000
• Euplotes telomerase contains an La motif protein produced by apparent translational frameshifting 2000
• Three conserved members of the RNase D family have unique and overlapping functions in the processing of 5S, 5.8S, U4, U5, RNase MRP and RNase P RNAs in yeast 2000
• Mechanism of rescue of common p53 cancer mutations by second-site suppressor mutations 2000
• Self-splicing of the Tetrahymena intron from mRNA in mammalian cells 1999
• The DCP2 protein is required for mRNA decapping in Saccharomyces cerevisiae and contains a functional MutT motif 1999
• Activation of the erythropoietin receptor by the gp55-P viral envelope protein is determined by a single amino acid in its transmembrane domain 1999
• The kinase suppressor of Ras (KSR) modulates growth factor and Ras signaling by uncoupling Elk-1 phosphorylation from MAP kinase activation 1998
• Comparative photocross-linking analysis of the tertiary structures of Escherichia coli and Bacillus subtilis RNase P RNAs 1998
• Isolation and characterization of Dcp1p, the yeast mRNA decapping enzyme 1998
• The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex 1998
• Functional crosstalk between exon enhancers, polypyrimidine tracts and branchpoint sequences. 1997
• Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins 1997
• Mutagenesis of a stacking contact in the MS2 coat protein-RNA complex 1996
• Specificity of hammerhead ribozyme cleavage 1996
• Mitochondrial import of only one of three nuclear-encoded glutamine tRNAs in Tetrahymena thermophila 1996
• dpa, a member of the MCM family, is required for mitotic DNA replication but not endoreplication in Drosophila. 1995
• RELATIVE ORIENTATION OF RNA HELICES IN A GROUP-I RIBOZYME DETERMINED BY HELIX EXTENSION ELECTRON-MICROSCOPY 1995
• 2 MAJOR TERTIARY FOLDING TRANSITIONS OF THE TETRAHYMENA CATALYTIC RNA 1994
• Two major tertiary folding transitions of the Tetrahymena catalytic RNA. 1994
• MANY OF THE CONSERVED NUCLEOTIDES OF TRNA(PHE) ARE NOT ESSENTIAL FOR TERNARY COMPLEX-FORMATION AND PEPTIDE ELONGATION 1994
• SELECTION FOR ACTIVE ESCHERICHIA-COLI TRANSFER RNA(PHE) VARIANTS FROM A RANDOMIZED LIBRARY USING 2 PROTEINS 1993
• REGULATION OF THE MEC-3-GENE BY THE C-ELEGANS HOMEOPROTEINS UNC-86 AND MEC-3 1992
• DISRUPTION OF THE YEAST NUCLEAR PET54-GENE BLOCKS EXCISION OF MITOCHONDRIAL INTRON AL5-BETA FROM PRE-MESSENGER RNA FOR CYTOCHROME-C OXIDASE SUBUNIT-I 1989
• A CONSERVED BASE PAIR WITHIN HELIX-P4 OF THE TETRAHYMENA RIBOZYME HELPS TO FORM THE TERTIARY STRUCTURE REQUIRED FOR SELF-SPLICING 1989
• DUAL TRANSLATIONAL INITIATION SITES CONTROL FUNCTION OF THE LAMBDA-S GENE 1989
• Mutations in concserved intron sequences affect multiple steps in the yeast splicing pathways, particularly assembly of the spliceosome 1986
• VIMENTIN AND KERATIN INTERMEDIATE FILAMENT SYSTEMS IN CULTURED PTK2 EPITHELIAL-CELLS ARE INTERRELATED 1982

Research

keywords

• 06 Biological Sciences, 08 Information and Computing Sciences, 11 Medical and Health Sciences