subject area of
- Alternative Modes of Binding of Poly(ADP-ribose) Polymerase 1 to Free DNA and Nucleosomes Journal Article
- Automodification switches PARP-1 function from chromatin architectural protein to histone chaperone Journal Article
- Combined EGFR1 and PARP1 Inhibition Enhances the Effect of Radiation in Head and Neck Squamous Cell Carcinoma Models Journal Article
- HPF1 and nucleosomes mediate a dramatic switch in activity of PARP1 from polymerase to hydrolase Journal Article
- Histone Parylation factor 1 contributes to the inhibition of PARP1 by cancer drugs Journal Article
- Kinetics of DNA-protein association and dissociation by stopped-flow spectroscopy Journal Article
- Nonspecific Binding of RNA to PARP1 and PARP2 Does Not Lead to Catalytic Activation Journal Article
- PARP inhibitors trap PARP2 and alter the mode of recruitment of PARP2 at DNA damage sites Journal Article
- PARP1 and HPF1 team up to flag down DNA-repair machinery Journal Article
- Poly(ADP-ribose) polymerase 1 searches DNA via a 'monkey bar' mechanism Journal Article
- Probing the Conformational Changes Associated with DNA Binding to PARP1 Journal Article
- Q-FADD: A Mechanistic Approach for Modeling the Accumulation of Proteins at Sites of DNA Damage Journal Article
- Quantitating repair protein accumulation at DNA lesions: Past, present, and future Journal Article
- Slow Dissociation from the PARP1-HPF1 Complex Drives Inhibitor Potency Journal Article
- Structural and Biophysical Studies of Human PARP-1 in Complex with Damaged DNA Journal Article
- The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer Journal Article