Telomere Replication Stress Induced by POT1 Inactivation Accelerates Tumorigenesis
Journal Article
Overview
publication date
- June 7, 2016
has subject area
- Animals
- Biochemical Phenomena - Amino Acid Sequence
- Biochemical Phenomena - DNA Repair
- Biochemical Phenomena - DNA Replication
- Biochemical Phenomena - Protein Binding
- Carrier Proteins - Ataxia Telangiectasia Mutated Proteins
- Carrier Proteins - Tumor Suppressor Protein p53
- Cells - Lymphoid Progenitor Cells
- DNA Damage
- DNA-Binding Proteins
- DNA-Binding Proteins - Telomere-Binding Proteins
- DNA-Binding Proteins - Tumor Suppressor Protein p53
- Disease Attributes - Genetic Predisposition to Disease
- Genetic Phenomena - DNA Repair
- Genetic Phenomena - DNA Replication
- Genetic Phenomena - Genomic Instability
- Genetic Structures - Telomere
- Genotype - Genetic Predisposition to Disease
- Hematopoietic System - Lymphoid Progenitor Cells
- Immunoproliferative Disorders - Lymphoma, T-Cell, Cutaneous
- Intranuclear Space - Telomere
- Lymphatic Diseases - Lymphoma, T-Cell, Cutaneous
- Lymphatic System - Thymus Gland
- Metabolism - Protein Binding
- Mice
- Molecular Sequence Data - Amino Acid Sequence
- Mutant Proteins
- Mutation
- Mutation - Genomic Instability
- Neoplasms - Carcinogenesis
- Neoplasms by Histologic Type - Lymphoma, T-Cell, Cutaneous
- Nuclear Proteins - Ataxia Telangiectasia Mutated Proteins
- Nuclear Proteins - Telomere-Binding Proteins
- Nuclear Proteins - Tumor Suppressor Protein p53
- Pathologic Processes - Carcinogenesis
- Pathologic Processes - Genomic Instability
- Phosphoproteins - Tumor Suppressor Protein p53
- Protein-Serine-Threonine Kinases - Ataxia Telangiectasia Mutated Proteins
- Stem Cells - Lymphoid Progenitor Cells
- Stress, Physiological
- Tissues - Thymus Gland
- Tumor Suppressor Proteins - Tumor Suppressor Protein p53
has restriction
- gold
Date in CU Experts
- May 31, 2016 12:59 PM
Full Author List
- Pinzaru AM; Hom RA; Beal A; Phillips AF; Ni E; Cardozo T; Nair N; Choi J; Wuttke DS; Sfeir A
author count
- 11
citation count
- 76
published in
- Cell Reports Journal
Other Profiles
International Standard Serial Number (ISSN)
- 2211-1247
Digital Object Identifier (DOI)
Additional Document Info
start page
- 2170
end page
- 2184
volume
- 15
issue
- 10