Disease Attributes - Genetic Predisposition to Disease
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subject area of
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DCDC2 is associated with reading disability and modulates neuronal development in the brain Journal Article
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A Critical Review of the First 10 Years of Candidate Gene-by-Environment Interaction Research in Psychiatry Journal Article
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A Preliminary Analysis of Interactions Between Genotype, Retrospective ADHD Symptoms, and Initial Reactions to Smoking in a Sample of Young Adults Journal Article
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A Recessive Genetic Model and Runs of Homozygosity in Major Depressive Disorder Journal Article
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A Risk Allele for Nicotine Dependence in CHRNA5 Is a Protective Allele for Cocaine Dependence Journal Article
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A comparison of the cognitive deficits in reading disability and attention-deficit/hyperactivity disorder Journal Article
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A computational language approach to modeling prose recall in schizophrenia Journal Article
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A genome-wide search for quantitative trait loci that influence antisocial drug dependence in adolescence Journal Article
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A novel genetic marker of decreased inflammation and improved survival after acute myocardial infarction Journal Article
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A twin study of drinking and smoking onset and latencies from first use to regular use Journal Article
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Acquired and innate cardioprotection Journal Article
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Additive Genetic Variation in Schizophrenia Risk Is Shared by Populations of African and European Descent Journal Article
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All SNPs Are Not Created Equal: Genome-Wide Association Studies Reveal a Consistent Pattern of Enrichment among Functionally Annotated SNPs Journal Article
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An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder. Journal Article
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An innate contribution of human nicotinic receptor polymorphisms to COPD-like lesions Journal Article
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Are Rumination and Neuroticism Genetically or Environmentally Distinct Risk Factors for Psychopathology? Journal Article
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Are endophenotypes based on measures of executive functions useful for molecular genetic studies of ADHD? Journal Article
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Association Analysis and Meta-Analysis of Multi-Allelic Variants for Large-Scale Sequence Data Journal Article
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Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts Journal Article
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Associations between Cannabinoid Receptor-1 (CNR1) Variation and Hippocampus and Amygdala Volumes in Heavy Cannabis Users Journal Article
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Attention-deficit/hyperactivity disorder endophenotypes Journal Article
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Bioinformatics assessment of beta-myosin mutations reveals myosin's high sensitivity to mutations Journal Article
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Biological insights from 108 schizophrenia-associated genetic loci Journal Article
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Case-control and within-family tests for an association between conduct disorder and 5HTTLPR Journal Article
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Case-control and within-family tests for an association between conduct disorder and DAT1 Journal Article
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Childhood maltreatment, subsequent antisocial behavior, and the role of monoamine oxidase A genotype Journal Article
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Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices Journal Article
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Cocaine'omics: Genome-wide and transcriptome-wide analyses provide biological insight into cocaine use and dependence Journal Article
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Cohort Effects in the Genetic Influence on Smoking Journal Article
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Collaborative analysis of DRD4 and DAT genotypes in population-defined ADHD subtypes Journal Article
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Common and Rare Variants Genetic Association Analysis of Cigarettes per Day Among Ever-Smokers in Chronic Obstructive Pulmonary Disease Cases and Controls Journal Article
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Common and drug-specific genetic influences on subjective effects to alcohol, tobacco and marijuana use Journal Article
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Common and specific genetic influences on aggressive and nonaggressive conduct disorder domains Journal Article
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Common variants in signaling transcription-factor-binding sites drive phenotypic variability in red blood cell traits Journal Article
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Confirmatory test of two factors and four subtypes of bipolar disorder based on lifetime psychiatric co-morbidity Journal Article
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Connecting genetic risk to disease end points through the human blood plasma proteome Journal Article
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Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects Journal Article
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DeFries-Fulker Analysis of Longitudinal Reading Performance Data from Twin Pairs Ascertained for Reading Difficulties and from Their Nontwin Siblings Journal Article
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Depression, Stressful Life Events, and the Impact of Variation in the Serotonin Transporter: Findings from the National Longitudinal Study of Adolescent to Adult Health (Add Health) Journal Article
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Developmental Effects of Serotonin 1A Autoreceptors on Anxiety and Social Behavior Journal Article
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Distinct Loci in the CHRNA5/CHRNA3/CHRNB4 Gene Cluster Are Associated With Onset of Regular Smoking Journal Article
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Dizziness and the genetic influences on subjective experiences to initial cigarette use Journal Article
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Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale Journal Article
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Dyslexia: nature and nurture. Journal Article
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EXAMINING THE SHARED ETIOLOGY OF PSYCHOPATHOLOGY WITH GENOME-WIDE ASSOCIATION STUDIES Journal Article
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Endophenotypes in the genetic analyses of mental disorders Journal Article
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Estimate of the abundance of cardiomyopathic mutations in the beta-myosin gene Journal Article
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Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs Journal Article
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Etiologies and Molecular Mechanisms of Communication Disorders Journal Article
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Evaluation of the Potential Excess of Statistically Significant Findings in Published Genetic Association Studies: Application to Alzheimer's Disease Journal Article
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Evidence for Association Between Low Frequency Variants in CHRNA6/CHRNB3 and Antisocial Drug Dependence Journal Article
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Evidence of Shared Genome-Wide Additive Genetic Effects on Interpersonal Trauma Exposure and Generalized Vulnerability to Drug Dependence in a Population of Substance Users Journal Article
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Evolution of immune genes is associated with the Black Death Journal Article
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Examining associations between disordered eating and serotonin transporter gene polymorphisms Journal Article
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Examining the role of common genetic variants on alcohol, tobacco, cannabis and illicit drug dependence: genetics of vulnerability to drug dependence Journal Article
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Executive Functions and Substance Use: Relations in Late Adolescence and Early Adulthood Journal Article
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Exploring How Symptoms of Attention-Deficit/Hyperactivity Disorder Are Related to Reading and Mathematics Performance: General Genes, General Environments Journal Article
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Exploring candidate gene associations with neuropsychological performance Journal Article
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Familial aggregation for conduct disorder symptomatology: the role of genes, marital discord and family adaptability Journal Article
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Family-based association test of the 5HTTLPR and aggressive behavior in a general population sample of children Journal Article
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Fine mapping of the chromosome 2p12-16 dyslexia susceptibility locus: quantitative association analysis and positional candidate genes SEMA4F and OTX1 Journal Article
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Functional Analyses of Endometriosis-Related Polymorphisms in the Estrogen Synthesis and Metabolism-Related Genes Journal Article
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Functional and structural assessment of retinal sheet allograft transplantation in feline hereditary retinal degeneration Journal Article
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GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium Journal Article
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Gene by environment interactions influencing reading disability and the inattentive symptom dimension of attention deficit/hyperactivity disorder Journal Article
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Gene expression imputation across multiple brain regions provides insights into schizophrenia risk Journal Article
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Gene x Environment Interaction Studies Have Not Properly Controlled for Potential Confounders: The Problem and the (Simple) Solution Journal Article
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Gene x environment interactions in speech sound disorder predict language and preliteracy outcomes Journal Article
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Gene-Environment Interplay in Common Complex Diseases: Forging an Integrative Model-Recommendations From an NIH Workshop Journal Article
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Genetic Architecture and Molecular Neuropathology of Human Cocaine Addiction Journal Article
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Genetic Association of the CHRNA6 and CHRNB3 Genes with Tobacco Dependence in a Nationally Representative Sample Journal Article
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Genetic Etiologies of Comorbidity and Stability for Reading Difficulties and ADHD: A Replication Study Journal Article
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Genetic Influences on Pubertal Development and Links to Behavior Problems Journal Article
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Genetic Schizophrenia Risk Variants Jointly Modulate Total Brain and White Matter Volume Journal Article
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Genetic analysis of low-dose ethanol-induced activation (LDA) in inbred long sleep (ILS) and inbred short sleep (ISS) mice Journal Article
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Genetic and environmental contributions to common psychopathologies of childhood and adolescence: A study of twins and their siblings Journal Article
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Genetic and environmental influences on antisocial behavior: A meta-analysis of twin and adoption studies Journal Article
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Genetic and environmental influences on orthographic and phonological skills in children with reading disabilities Journal Article
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Genetic and environmental influences on substance initiation, use, and problem use in adolescents Journal Article
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Genetic architecture of 11 major psychiatric disorders at biobehavioral, functional genomic and molecular genetic levels of analysis Journal Article
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Genetic architecture of four smoking behaviors using partitioned SNP heritability Journal Article
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Genetic dissection of quantitative trait locus for ethanol sensitivity in long- and short-sleep mice Journal Article
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Genetic diversity fuels gene discovery for tobacco and alcohol use Journal Article
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Genetic etiology of the common liability to drug dependence: Evidence of common and specific mechanisms for DSM-IV dependence symptoms Journal Article
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Genetic influences on ADHD symptom dimensions: Examination of a priori candidates, gene-based tests, genome-wide variation, and SNP heritability Journal Article
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Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs Journal Article
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Genetic variation links creativity to psychiatric disorders Journal Article
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Genome-Wide Association Study of Behavioral Disinhibition in a Selected Adolescent Sample Journal Article
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Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences Journal Article
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Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence Journal Article
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Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia Journal Article
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Genome-wide association study identifies five new schizophrenia loci Journal Article
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Genome-wide association study reveals new insights into the heritability and genetic correlates of developmental dyslexia Journal Article
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Genome-wide single nucleotide polymorphism heritability of nicotine dependence as a multidimensional phenotype Journal Article
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Genomewide weighted hypothesis testing in family-based association studies, with an application to a 100K scan Journal Article
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Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders Journal Article
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Human gamma-aminobutyric acid A receptor alpha 2 gene moderates the acute effects of alcohol and brain mRNA expression Journal Article
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Identical and Nonidentical Twins: Risk and Factors Involved in Development of Islet Autoimmunity and Type 1 Diabetes Journal Article
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Identification of Candidate Genes for Dyslexia Susceptibility on Chromosome 18 Journal Article
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Improved Detection of Common Variants Associated with Schizophrenia by Leveraging Pleiotropy with Cardiovascular-Disease Risk Factors Journal Article
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Increased Genetic Vulnerability to Smoking at CHRNA5 in Early-Onset Smokers Journal Article
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Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment Journal Article
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Inherited causes of clonal haematopoiesis in 97,691 whole genomes Journal Article
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Insights into Human beta-Cardiac Myosin Function from Single Molecule and Single Cell Studies Journal Article
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Integrated analysis of direct and proxy genome wide association studies highlights polygenicity of Alzheimer's disease outside of the APOE region Journal Article
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Interaction between MAO-A genotype and maltreatment in the risk for conduct disorder: Failure to confirm in adolescent patients Journal Article
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Interaction of prenatal exposure to cigarettes and MAOA genotype in pathways to youth antisocial behavior Journal Article
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Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets Journal Article
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Large-scale genomics unveils the genetic architecture of psychiatric disorders Journal Article
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Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium Journal Article
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Life events, genetic susceptibility, and smoking among adolescents Journal Article
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Linkage Disequilibrium Mapping of The Chromosome 6q21-22.31 Bipolar I Disorder Susceptibility Locus Journal Article
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Little Evidence of Modified Genetic Effect of rs16969968 on Heavy Smoking Based on Age of Onset of Smoking Journal Article
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MAOA Genotype, Childhood Maltreatment, and Their Interaction in the Etiology of Adult Antisocial Behaviors Journal Article
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Mapping genomic loci implicates genes and synaptic biology in schizophrenia Journal Article
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Mapping of an autoimmunity susceptibility locus (AIS1) to chromosome 1p31.3-p32.2 Journal Article
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Meta-analysis of genome-wide association studies of anxiety disorders Journal Article
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Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT) Journal Article
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Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018) Journal Article
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Multiple Distinct Risk Loci for Nicotine Dependence Identified by Dense Coverage of the Complete Family of Nicotinic Receptor Subunit (CHRN) Genes Journal Article
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Multivariate genome-wide association study of rapid automatised naming and rapid alternating stimulus in Hispanic American and African-American youth Journal Article
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Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 Are Identified in Individuals with Congenital Hypogonadotropic Hypogonadism Journal Article
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New Approaches to Identifying Rare Genetic Variants Associated with Nicotine Dependence Journal Article
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New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. Journal Article
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No Evidence That Schizophrenia Candidate Genes Are More Associated With Schizophrenia Than Noncandidate Genes Journal Article
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No association between MspI allele of the ADRA2A polymorphism and ADHD: meta-analysis of family-based studies Journal Article
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On the parsing of statistical information in family-based association testing Journal Article
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On the replication of genetic associations:: Timing can be everything! Journal Article
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Perceived peer delinquency and the genetic predisposition for substance dependence vulnerability Journal Article
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Personality Dimensions as Common and Broadband-Specific Features for Internalizing and Externalizing Disorders Journal Article
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Phenotypic and genetic factors in motives for smoking Journal Article
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Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways Journal Article
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Population stratification in the candidate gene study: Fatal threat or red herring? Journal Article
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Post-GWAS analysis of six substance use traits improves the identification and functional interpretation of genetic risk loci Journal Article
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Predicting causal genes from psychiatric genome-wide association studies using high-level etiological knowledge Journal Article
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Psychiatric comorbidity in children and adolescents with reading disability Journal Article
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Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways Journal Article
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Quantitative trait locus for reading disability on chromosome 6p is pleiotropic for attention-deficit hyperactivity disorder Journal Article
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REDUCED Chrna7 EXPRESSION IN MICE IS ASSOCIATED WITH DECREASES IN HIPPOCAMPAL MARKERS OF INHIBITORY FUNCTION: IMPLICATIONS FOR NEUROPSYCHIATRIC DISEASES Journal Article
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Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans Journal Article
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Reading disability: Evidence for a genetic etiology Journal Article
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Recent methods for polygenic analysis of genome-wide data implicate an important effect of common variants on cardiovascular disease risk Journal Article
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Research on environmental effects in genetic studies of aging - Comments Journal Article
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Resolving the paradox of common, harmful, heritable mental disorders: Which evolutionary genetic models work best? Journal Article
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Right ventricular function and failure - Report of a National Heart, lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure Journal Article
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Runs of Homozygosity Implicate Autozygosity as a Schizophrenia Risk Factor Journal Article
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SNPs in CHRNA6 and CHRNB3 are associated with alcohol consumption in a nationally representative sample Journal Article
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Sensation Seeking, Peer Deviance, and Genetic Influences on Adolescent Delinquency: Evidence for Person-Environment Correlation and Interaction Journal Article
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Sequence diversity analyses of an improved rhesus macaque genome enhance its biomedical utility Journal Article
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Serotonin transporter gene, stress and raphe-raphe interactions: a molecular mechanism of depression Journal Article
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Setting priorities for genomic research Journal Article
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Sibling-based association analyses of the serotonin transporter polymorphism and internalizing behavior problems in children Journal Article
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Simple Sequence Repeats in the National Longitudinal Study of Adolescent Health: An Ethnically Diverse Resource for Genetic Analysis of Health and Behavior Journal Article
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Social disorder, APOE-E4 genotype, and change in cognitive function among older adults living in Chicago Journal Article
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Stressful Life Events and Depression among Adolescent Twin Pairs Journal Article
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Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function Journal Article
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Sun exposure, vitamin D receptor polymorphisms FokI and BsmI and risk of multiple primary melanoma Journal Article
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Susceptibility to Phytophthora ramorum in a key infectious host: landscape variation in host genotype, host phenotype, and environmental factors. Journal Article
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Susceptibility to glaucoma: differential comparison of the astrocyte transcriptome from glaucomatous African American and Caucasian American donors Journal Article
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Symptom-level modelling unravels the shared genetic architecture of anxiety and depression Journal Article
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Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database Journal Article
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Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database Journal Article
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Telomere Replication Stress Induced by POT1 Inactivation Accelerates Tumorigenesis Journal Article
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Test of alternative hypotheses explaining the comorbidity between attention-deficit/hyperactivity disorder and conduct disorder Journal Article
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Testing for neuropsychological endophenotypes in siblings discordant for attention-deficit/hyperactivity disorder Journal Article
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The Aromatase Gene CYP19A1: Several Genetic and Functional Lines of Evidence Supporting a Role in Reading, Speech and Language Journal Article
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The Association Between Toddlerhood Self-Control and Later Externalizing Problems Journal Article
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The CHRNA5/A3/B4 Gene Cluster and Tobacco, Alcohol, Cannabis, Inhalants and Other Substance Use Initiation: Replication and New Findings Using Mixture Analyses Journal Article
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The CHRNA5/A3/B4 gene cluster variability as an important determinant of early alcohol and tobacco initiation in young adults Journal Article
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The MUC5B-associated variant rs35705950 resides within an enhancer subject to lineage- and disease-dependent epigenetic remodeling Journal Article
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The National Longitudinal Study of Adolescent to Adult Health (Add Health) Sibling Pairs Genome-Wide Data Journal Article
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The Speed of Progression to Tobacco and Alcohol Dependence: A Twin Study Journal Article
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The dynamic epigenome and its implications for behavioral interventions: a role for epigenetics to inform disorder prevention and health promotion Journal Article
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The functional serotonin 1a receptor promoter polymorphism, rs6295, is associated with psychiatric illness and differences in transcription Journal Article
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The human protein kinase C gamma gene (PRKCG) as a susceptibility locus for behavioral disinhibition Journal Article
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The role of genetic and environmental influences on the association between childhood ADHD symptoms and BMI Journal Article
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The shared genetic architecture of modifiable risk for Alzheimer's disease: a genomic structural equation modelling study Journal Article
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Trans-ancestry meta-analysis of genome wide association studies of inhibitory control Journal Article
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Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders Journal Article
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Transcriptome-Wide Structural Equation Modeling of 13 Major Psychiatric Disorders for Cross-Disorder Risk and Drug Repurposing Journal Article
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Transcriptome-wide association study and eQTL colocalization identify potentially causal genes responsible for human bone mineral density GWAS associations Journal Article
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Twin studies to GWAS: there and back again Journal Article
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Understanding comorbidity: A twin study of reading disability and attention-deficit/hyperactivity disorder Journal Article
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Understanding the Complex Etiologies of Developmental Disorders: Behavioral and Molecular Genetic Approaches Journal Article
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Varieties of developmental reading disorder: Genetic and environmental influences Journal Article
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What can genes tell us about the relationship between education and health? Journal Article
broader concept