Dietary rapamycin supplementation reverses age-related vascular dysfunction and oxidative stress, while modulating nutrient-sensing, cell cycle, and senescence pathways
Journal Article
Overview
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Adenylate Kinase
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Aging
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Animals
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Animals, Inbred Strains - Mice, Inbred C57BL
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Arteries
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Biomarkers
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Blood Glucose
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Cell Cycle
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Cell Cycle Proteins
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Cellular Senescence
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Diet, Food, and Nutrition - Dietary Supplements
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Drug Resistance - Insulin Resistance
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Endothelium - Endothelium, Vascular
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Food and Beverages - Dietary Supplements
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Growth - Body Weight
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Growth - Organ Size
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Homeostasis
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Hormones, Hormone Substitutes, and Hormone Antagonists - Insulin
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Hyperinsulinism - Insulin Resistance
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Investigative Techniques - Body Weight
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Investigative Techniques - Organ Size
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Male
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Metabolism - Oxidative Stress
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Mice - Mice, Inbred C57BL
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Peptides - Insulin
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Physical Examination - Body Weight
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Physical Examination - Organ Size
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Physiological Phenomena - Body Weight
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Physiological Phenomena - Organ Size
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Protein-Serine-Threonine Kinases - TOR Serine-Threonine Kinases
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Proteins - TOR Serine-Threonine Kinases
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Signs and Symptoms - Body Weight
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Sirolimus
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Stress, Physiological - Oxidative Stress
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Tunica Intima - Endothelium, Vascular
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Vascular Stiffness
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Vasodilation
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Date in CU Experts
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September 30, 2016 1:43 AM
Full Author List
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Lesniewski LA; Seals DR; Walker AE; Henson GD; Blimline MW; Trott DW; Bosshardt GC; LaRocca TJ; Lawson BR; Zigler MC
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