Histone chaperone FACT FAcilitates Chromatin Transcription: mechanistic and structural insights. Journal Article uri icon



  • The histone chaperone FACT (FAcilitates Chromatin Transcription) modulates nucleosome structure during many processes requiring access to chromatinized DNA. Here, we review recent biochemical and structural insight into how FACT acts in both nucleosome assembly and disassembly, to maintain chromatin structure while DNA is being worked on by polymerases.

publication date

  • June 20, 2020

Full Author List

  • Zhou K; Liu Y; Luger K

Other Profiles

Additional Document Info

start page

  • 26

end page

  • 32


  • 65