Switching gears: translational mastery of transcription during memory formation. Journal Article uri icon

Overview

abstract

  • A critical molecular requirement underlying many forms of long-lasting synaptic plasticity and memory is the de novo synthesis of mRNAs and proteins. In a recent paper in Cell, Costa-Mattioli et al. present data from a pharmacogenetic study that places a key regulatory event in the "neural decision" to undergo these persistent neuronal changes under translational control mediated by eIF2alpha.

publication date

  • April 1, 2007

Full Author List

  • Hoeffer CA; Klann E

published in

Other Profiles

Additional Document Info

start page

  • 186

end page

  • 189

volume

  • 54

issue

  • 2