Prof. Sievers, his students, and collaborators have patented, developed, and commercialized the Bubble Dryer®, turn-key equipment which allows the rapid low temperature drying of vaccines. Other research on sublingual delivery of vaccines and pharmaceuticals has led to the publication by the US Patent Office of new claims for US Pat App 20130202655 and 20160228385 in 2016. Sievers has collaborated with medical professionals to develop new methods for delivery of aerosol particles useful in direct and painless administration of therapueutic drugs and vaccines against measles, Influenza, infections, stress, pain, and asthma. Two of the fourteen 'Grand Challenges' identified by the Gates Foundation as critical to world health have been addressed. In technology transfer, Sievers Instruments, Inc. and successor companies, Ionics-Sievers and GE Analytical, have manufactured 30,000 detectors and analyzers for 10,000 users for applications in trace analysis from 1984 to present.
purification and separation chemistry, graphene, sublingual pharmaceutical delivery, aerosol vaccine delivery, dry powder measles vaccine, pulmonary drug delivery, stabilization and delivery, synthesis of 1-µm diameter pharmaceutical particles, environmental chemistry, trace analysis of air and water, gas and liquid chromatography, aerosols, supercritical fluid technology, spray bubble drying, sublingual drug delivery, inhalable antibiotics, inhalable nutraceuticals