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Singh, Ravinder Associate Professor

Positions

Research Areas research areas

Research

research overview

  • Dr. Singh's laboratory studies post-transcriptional gene regulation. The focus is on how RNA-binding proteins control molecular processes during male and female germline stem cell differentiation and tounderstand the basis for the Down syndrome. They use Drosophila, fission yeast, and cultured cells as model organisms or systems and involve a combination of computational, biochemical, molecular and genetic approaches to address the basis of specificity, which is the key aspect of gene regulation.

Publications

selected publications

Teaching

courses taught

  • MCDB 3135 - Molecular Cell Biology I
    Primary Instructor - Spring 2018 / Summer 2018
    Examines the central dogma of biology by discussing the most important molecules in cells (DNA, RNA and protein) and how their synthesis (DNA replication, transcription, RNA processing and translation) is regulated. Incorporated into the discussion is how recombinant DNA techniques are used to discover and dissect cellular processes, how to design and interpret experiments, and understanding the limits of experiments to draw conclusions. These principles are the foundation for subsequent examination of intracellular mechanisms in MCDB 3145.
  • MCDB 3333 - Biomedical Innovations and Discoveries
    Primary Instructor - Fall 2018 / Fall 2019
    Discusses how biological inventions and discoveries fuel biomedical innovations, how important techniques in molecular biology have advanced our understanding of cellular processes and contributed to biotechnology revolution and biomedical sciences to benefit our society. Guest lectures from experts in industry and site visits will enhance the course by providing a non-academic perspective, networking opportunities, and unexpected avenues for career paths for our graduates. Department enforced prerequisite: MCDB 2150 or EBIO 2070 or instructor consent.
  • MCDB 4471 - Mechanisms of Gene Regulation in Eukaryotes
    Primary Instructor - Spring 2018 / Fall 2019
    Focuses on manifestations of regulated gene expression. Studies gene regulation at multiple steps, including transcription, RNA processing and translation. Is based on critical analysis of primary research papers. Written assignments and oral presentations are required. Fulfills MCDB scientific reasoning requirement. Recommended prerequisite: MCDB 3135 (minimum grade C-) or instructor consent required. Same as MCDB 5471.
  • MCDB 4980 - Honors Research
    Primary Instructor - Fall 2019
    Provides faculty-supervised research for students who have been approved by the departmental honors committee. Normally taken during the semester before completion of the honors thesis. Recommended prerequisite: MCDB 4840 or comparable research experience, and minimum GPA of 3.20.
  • MCDB 4990 - Honors Thesis
    Primary Instructor - Fall 2019
    Involves the preparation and defense of an honors thesis, based on faculty-supervised original research, including final phases of the research project. Recommended prerequisites: MCDB 4840 or MCDB 4980 or comparable research experience, and minimum GPA of 3.3 and approval by the MCDB Honors Committee.
  • MCDB 5230 - Graduate Core 1
    Primary Instructor - Fall 2018
  • MCDB 5471 - Mechanisms of Gene Regulation in Eukaryotes
    Primary Instructor - Spring 2018 / Fall 2019
    Focuses on manifestations of regulated gene expression. Studies gene regulation at multiple steps, including transcription, RNA processing and translation. Is based on critical analysis of primary research papers. Written assignments and oral presentations are required. Same as MCDB 4471.

Background

Other Profiles