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Publications in VIVO
 

DeDecker, Brian S Senior Instructor

Positions

Research Areas research areas

Research

research overview

  • Our research efforts are focused on developing techniques and tools for the field of synthetic biology. For instance, biologics are protein based therapeutics that can be engineered with remarkable specificity using these tools. To this end, we have developed a new gene synthesis method for the constitution of variable protein libraries (Lee et al.). We are currently developing additional methods and strategies to engineer biological systems.

keywords

  • Synthetic Biology

Publications

selected publications

Teaching

courses taught

  • CHEN 3000 - Synthetic Biology: Engineering Biomolecular Systems in the Laboratory
    Primary Instructor - Spring 2020
    Hands-on research experience in engineering biological systems. Students will design biological systems to address relevant medical and environmental problems facing our society. They will learn how to build their molecular designs in the lab using current synthetic biology techniques. Students will also learn how to critically evaluate current research in the field and effectively communicate their own research. Formerly offered as a special topics course. Recommended Restriction: BCHM, ENGR and BCHM majors only.
  • MCDB 1030 - Introduction to Molecular Biology
    Primary Instructor - Fall 2018 / Fall 2019 / Fall 2020 / Fall 2021
    Introduces the foundation of molecular, cell, developmental and evolutionary biology in the context of human development and disease. Including how the immune system works to protect us from infections and technologies being developed towards the goal of better health around the world. For nonmajors.
  • MCDB 3000 - Synthetic Biology: Engineering Biomolecular Systems in the Laboratory
    Primary Instructor - Spring 2020 / Spring 2021 / Fall 2021
    Hands-on research experience in engineering biological systems. Students will design biological systems to address relevant medical and environmental problems facing our society. They will learn how to build their molecular designs in the lab using current synthetic biology techniques. Students will also learn how to critically evaluate current research in the field and effectively communicate their own research. Formerly offered as a special topics course.
  • MCDB 4100 - Special Topics
    Primary Instructor - Spring 2018 / Spring 2019 / Spring 2020
    May be repeated up to 6 total credit hours. Recommended prerequisites: MCDB 3135 and MCDB 3145 (minimum grade C-).
  • MCDB 4361 - Evolution and Development
    Primary Instructor - Spring 2018 / Spring 2020
    Relates how recent discoveries in the molecular mechanisms of development are shaping our understanding of animal evolution. Reviews basic principles of molecular developmental biology and applies these concepts to critically discuss current research in the field of Evo-Devo (evolution and development). Fulfills MCDB scientific reasoning requirement. Recommended prerequisites: MCDB 3135 and MCDB 3145 (minimum grade C-). Same as MCDB 5361.
  • MCDB 4800 - Molecular Evolution: How Natural Selection has Shaped the Molecules of Life
    Primary Instructor - Spring 2021
    This course explores how Darwin's idea has shaped the structures of DNA, RNA and proteins across the long history of life on earth. Natural selection driving the evolution these macromolecules and subsequent developmental pathways will be fully appreciated as the process that ultimately produced the amazing variety of species on this planet. Looking ahead, our recent efforts to harness the power of evolution in the test tube to develop new therapies will be covered.
  • MCDB 4990 - Honors Thesis
    Primary Instructor - Spring 2018 / Spring 2019
    Involves the preparation and defense of an honors thesis, based on faculty-supervised original research, including final phases of the research project. Recommended prerequisites: MCDB 4840 or MCDB 4980 or comparable research experience, and minimum GPA of 3.3 and approval by the MCDB Honors Committee.

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