C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins
Journal Article
Overview
publication date
- May 1, 2016
has subject area
- Animals
- Atrophy
- Behavior, Animal
- Brain
- Brain Diseases - Frontotemporal Dementia
- C9orf72 Protein
- Carrier Proteins
- Cells - Neurons
- Culture Techniques - Primary Cell Culture
- DNA-Binding Proteins
- Diagnostic Techniques and Procedures - Primary Cell Culture
- Gene Expression
- Humans
- Inclusion Bodies
- Investigative Techniques - Primary Cell Culture
- Investigative Techniques - Primary Cell Culture
- Mice
- Mutation
- Nerve Degeneration
- Nervous System - Neurons
- Neurocognitive Disorders - Frontotemporal Dementia
- Neurodegenerative Diseases - Amyotrophic Lateral Sclerosis
- Neurodegenerative Diseases - Amyotrophic Lateral Sclerosis
- Neurodegenerative Diseases - Frontotemporal Dementia
- Neuromuscular Diseases - Amyotrophic Lateral Sclerosis
- Peptides - Guanine Nucleotide Exchange Factors
- Proteins
- Proteins - Guanine Nucleotide Exchange Factors
- Proteostasis Deficiencies - Amyotrophic Lateral Sclerosis
- Proteostasis Deficiencies - Frontotemporal Dementia
- Spinal Cord Diseases - Amyotrophic Lateral Sclerosis
- Ubiquitinated Proteins
has restriction
- green
Date in CU Experts
- March 25, 2016 12:22 PM
Full Author List
- Zhang Y-J; Gendron TF; Grima JC; Sasaguri H; Jansen-West K; Xu Y-F; Katzman RB; Gass J; Murray ME; Shinohara M
author count
- 36
citation count
- 227
published in
- Nature Neuroscience Journal
Other Profiles
International Standard Serial Number (ISSN)
- 1097-6256
Electronic International Standard Serial Number (EISSN)
- 1546-1726
Digital Object Identifier (DOI)
Additional Document Info
start page
- 668
end page
- +
volume
- 19
issue
- 5