Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant. Journal Article uri icon

Overview

abstract

  • The first centromeric protein identified in any species was CENP-A, a divergent member of the histone H3 family that was recognised by autoantibodies from patients with scleroderma-spectrum disease. It has recently been suggested to rename this protein CenH3. Here, we argue that the original name should be maintained both because it is the basis of a long established nomenclature for centromere proteins and because it avoids confusion due to the presence of canonical histone H3 at centromeres.

publication date

  • April 1, 2013

Full Author List

  • Earnshaw WC; Allshire RC; Black BE; Bloom K; Brinkley BR; Brown W; Cheeseman IM; Choo KHA; Copenhaver GP; Deluca JG

Other Profiles

Additional Document Info

start page

  • 101

end page

  • 106

volume

  • 21

issue

  • 2