Experimental autoimmune encephalopathy (EAE)-induced hippocampal neuroinflammation and memory deficits are prevented with the non-opioid TLR2/TLR4 antagonist (+)-naltrexone
Journal Article
Overview
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Animals
Autoimmune Diseases - Encephalomyelitis, Autoimmune, Experimental
Autoimmune Diseases - Multiple Sclerosis
Behavior and Behavior Mechanisms - Memory Disorders
Behavior, Animal
Cells - Microglia
Cells, Cultured
Central Nervous System Agents - Narcotic Antagonists
Cerebral Cortex - Hippocampus
Conditioning, Classical
Demyelinating Diseases - Encephalomyelitis, Autoimmune, Experimental
Demyelinating Diseases - Multiple Sclerosis
Fear
Heterocyclic Compounds, 4 or More Rings - Naltrexone
Heterocyclic Compounds, Bridged-Ring - Naltrexone
Inflammation
Leukoencephalopathies - Encephalomyelitis, Autoimmune, Experimental
Limbic System - Hippocampus
Male
Mice
Models, Animal - Encephalomyelitis, Autoimmune, Experimental
Nervous System - Microglia
Nervous System Diseases - Encephalomyelitis, Autoimmune, Experimental
Nervous System Diseases - Memory Disorders
Nervous System Diseases - Multiple Sclerosis
Opiate Alkaloids - Naltrexone
Physiological Effects of Drugs - Narcotic Antagonists
Polycyclic Compounds - Naltrexone
Rats
Rats, Sprague-Dawley
Sensory System Agents - Narcotic Antagonists
Signs and Symptoms - Memory Disorders
Toll-Like Receptor 2
Toll-Like Receptor 4
has restriction
Date in CU Experts
September 10, 2020 5:46 AM
Full Author List
Kwilasz AJ; Todd LS; Duran-Malle JC; Schrama AEW; Mitten EH; Larson TA; Clements MA; Harris KM; Litwiler ST; Wang X
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