Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA. Journal Article uri icon

Overview

abstract

  • The three N-terminal zinc fingers of transcription factor IIIA bind in the DNA major groove. Substantial packing interfaces are formed between adjacent fingers, the linkers lose their intrinsic flexibility upon DNA binding, and several lysine side chains implicated in DNA recognition are dynamically disordered.

publication date

  • August 1, 1997

has subject area

Full Author List

  • Foster MP; Wuttke DS; Radhakrishnan I; Case DA; Gottesfeld JM; Wright PE

Other Profiles

Additional Document Info

start page

  • 605

end page

  • 608

volume

  • 4

issue

  • 8