research overview
- Dr. Singh's laboratory studies post-transcriptional gene regulation. The focus is on how RNA-binding proteins control molecular processes during male and female germline stem cell differentiation and to understand the basis for the Down syndrome. His lab uses Drosophila, fission yeast, and cultured cells as model organisms or systems and involves a combination of computational, biochemical, molecular and genetic approaches to address the basis of specificity, which is the key aspect of gene regulation.