Molecular Cell Journal

Overview

publication venue for

• Phages gain the upper hand in the metabolic arms race for NAD 2024
• G3BP1 promotes intermolecular RNA-RNA interactions during RNA condensation. 2024
• PRC2-RNA interactions: Viewpoint from Tom Cech, Chen Davidovich, and Richard Jenner 2024
• Transcription regulation through selective partitioning: Weak interactions with a strong foundation 2024
• Shining light on DHX9: UV-induced stress granules illuminate protective mechanisms for daughter cell resilience 2024
• Changing structures, changing paradigms NELF helps regulate paused or elongating RNA polymerase II 2024
• The APE2 nuclease is essential for DNA double-strand break repair by microhomology-mediated end joining 2023
• The complexity of transferring genetic information. 2023
• 25 years since the high-resolution structure of the nucleosome: An interview with Dr. Karolin Luger 2022
• The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer 2021
• Competition between PRC2.1 and 2.2 subcomplexes regulates PRC2 chromatin occupancy in human stem cells 2021
• TFIID Enables RNA Polymerase II Promoter-Proximal Pausing 2020
• Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity 2020
• Mediator Condensates Localize Signaling Factors to Key Cell Identity Genes 2019
• Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions 2019
• RNase L Reprograms Translation by Widespread mRNA Turnover Escaped by Antiviral mRNAs 2019
• The RNase PARN Controls the Levels of Specific miRNAs that Contribute to p53 Regulation 2019
• Inter-chromosomal Contact Properties in Live-Cell Imaging and in Hi-C (vol 69, pg 1039, 2018) 2018
• Inter-chromosomal Contact Properties in Live-Cell Imaging and in Hi-C 2018
• The Stress Granule Transcriptome Reveals Principles of mRNA Accumulation in Stress Granules 2017
• The Continuing SAGA of TFIID and RNA Polymerase II Transcription 2017
• Targeting of Polycomb Repressive Complex 2 to RNA by Short Repeats of Consecutive Guanines 2017
• PARP1 and Sox2: An Unlikely Team of Pioneers to Conquer the Nucleosome 2017
• "Cat's Cradling'' the 3D Genome by the Act of LncRNA Transcription 2016
• Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins 2015
• Architecture of the Human and Yeast General Transcription and DNA Repair Factor TFIIH 2015
• All in the Family: A Portrait of a Nuclear Receptor Co-Activator Complex 2015
• Toward a Consensus on the Binding Specificity and Promiscuity of PRC2 for RNA 2015
• Principles and Properties of Eukaryotic mRNPs 2014
• Fragile X Mental Retardation Protein and the Ribosome 2014
• Back to Bases: How a Nucleotide Biosynthetic Enzyme Controls p53 Activation 2014
• Chaperone Nap1 Shields Histone Surfaces Used in a Nucleosome and Can Put H2A-H2B in an Unconventional Tetrameric Form 2013
• TOR-tured yeast find a new way to stand the heat. 2012
• Systematic Analysis of Tissue-Restricted miRISCs Reveals a Broad Role for MicroRNAs in Suppressing Basal Activity of the C. elegans Pathogen Response 2012
• Get Back TFIIF, Don't Let Me Gdown1 2012
• Scd6 Targets eIF4G to Repress Translation: RGG Motif Proteins as a Class of eIF4G-Binding Proteins 2012
• The DEAD-Box Protein Ded1 Modulates Translation by the Formation and Resolution of an eIF4F-mRNA Complex 2011
• The Meaning of Pausing 2010
• Decapping Activators in Saccharomyces cerevisiae Act by Multiple Mechanisms 2010
• The Histone Chaperone Nap1 Promotes Nucleosome Assembly by Eliminating Nonnucleosomal Histone DNA Interactions 2010
• Chaperoning of a Replicative Polymerase onto a Newly Assembled DNA-Bound Sliding Clamp by the Clamp Loader 2010
• The Case of the Disappearing Drug Target 2010
• Reconstitution of the B-subtilis Replisome with 13 Proteins Including Two Distinct Replicases 2010
• Eukaryotic Stress Granules: The Ins and Outs of Translation 2009
• Related Mechanisms for mRNA and rRNA Quality Control 2009
• Functional Proteomics Identifies Targets of Phosphorylation by B-Raf Signaling in Melanoma 2009
• Transcriptional regulation: It takes a village 2008
• Caenorhabditis elegans drp-1 and fis-2 regulate distinct cell-death execution pathways downstream of ced-3 and independent of ced-9 2008
• Different aa-tRNAs are selected uniformly on the ribosome. 2008
• Human Alu RNA is a modular transacting repressor of mRNA transcription during heat shock 2008
• Structural Basis of Dcp2 Recognition and Activation by Dcp1 2008
• Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2 2007
• Docking of the Proteasomal ATPases' Carboxyl Termini in the 20S Proteasome's α Ring Opens the Gate for Substrate Entry 2007
• Unlocking the Proteasome Door 2007
• CDK8 is a stimulus-specific positive coregulator of p53 target genes 2007
• P Bodies and the Control of mRNA Translation and Degradation 2007
• Structure and function of eukaryotic ribonuclease P RNA 2006
• When to believe what you see. 2006
• Beating the heat: A translation factor and an RNA mobilize the heat shock transcription factor HSF1 2006
• Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping 2005
• The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in C. elegans 2005
• Uniform binding of aminoacylated transfer RNAs to the ribosomal A and P sites. 2004
• H2A.Z alters the nucleosome surface to promote HP1α-mediated chromatin fiber folding 2004
• Structure of the Tetrahymena ribozyme:: Base triple sandwich and metal ion at the active site 2004
• Structural, biochemical, and functional analyses of CED-9 recognition by the proapoptotic proteins EGL-1 and CED-4 2004
• Crystal structure of Skp, a prefoldin-like chaperone that protects soluble and membrane proteins from aggregation 2004
• A unified nomenclature for protein subunits of Mediator complexes linking transcriptional regulators to RNA polymerase II 2004
• Structure and function of CRSP/Med2: A promoter-selective transcriptional coactivator complex 2004
• Docking motif interactions in MAP kinases revealed by hydrogen exchange mass spectrometry 2004
• Cytoplasmic Degradation of Splice-Defective Pre-mRNAs and Intermediates 2003
• Functional genomic analysis of apoptotic DNA degradation in C-elegans 2003
• Targeting an mRNA for Decapping 2001
• The anaphase-promoting complex mediates TGF-β signaling by targeting SnoN for destruction 2001
• Identification of novel MAP kinase pathway signaling targets by functional proteomics and mass spectrometry 2000
• Telomerase RNA bound by protein motifs specific to telomerase reverse transcriptase 2000
• Interaction of the Ski oncoprotein with Smad3 regulates TGF-β signaling 1999
• Regulation of Wnt signaling by sox proteins:: XSox17α/β and XSox3 physically interact with β-catenin 1999

Research

keywords

• 06 Biological Sciences, 11 Medical and Health Sciences