Polycyclic Compounds - Doxorubicin PubMed MeSh Term

Overview

subject area of

• A redox pathway leading to the alkylation of nucleic acids by doxorubicin and related anthracyclines: Application to the design of antitumor drugs for resistant cancer  Journal Article
• Accelerated aging of the brain transcriptome by the common chemotherapeutic doxorubicin  Journal Article
• Alkylation of DNA by the anthracycline, antitumor drugs adriamycin and daunomycin  Journal Article
• Antiestrogen binding site and estrogen receptor mediate uptake and distribution of 4-hydroxytamoxifen-targeted doxorubicin-formaldehyde conjugate in breast cancer cells.  Journal Article
• CDK8 is a stimulus-specific positive coregulator of p53 target genes  Journal Article
• Carboxylesterase-2 is a highly sensitive target of the antiobesity agent orlistat with profound implications in the activation of anticancer prodrugs  Journal Article
• Chemical ionization mass spectrometric determination of acrolein in human breast cancer cells  Journal Article
• Click Nucleic Acid Mediated Loading of Prodrug Activating Enzymes in PEG-PLGA Nanoparticles for Combination Chemotherapy  Journal Article
• DOXORUBICIN-INDUCED SKIN NECROSIS IN THE SWINE MODEL - PROTECTION WITH A NOVEL RADICAL DIMER  Journal Article
• Design principles of drug combinations for chemotherapy  Journal Article
• Design, synthesis, and biological evaluation of doxorubicin - Formaldehyde conjugates targeted to breast cancer cells  Journal Article
• Design, synthesis, and preliminary evaluation of doxazolidine carbamates as prodrugs activated by carboxylesterases  Journal Article
• Doxazolidine induction of apoptosis by a topoisomerase II independent mechanism  Journal Article
• Doxazolidine, a proposed active metabolite of doxorubicin that cross-links DNA  Journal Article
• Doxoform and daunoform: Anthracycline-formaldehyde conjugates toxic to resistant tumor cells  Journal Article
• Doxorubicin impacts chromatin binding of HMGB1, Histone H1 and retinoic acid receptor  Journal Article
• Doxorubicin-formaldehyde conjugate, Doxoform: Induction of apoptosis relative to doxorubicin  Journal Article
• Doxorubicin-formaldehyde conjugates targeting α_vβ₃ integrin  Journal Article
• EXPERIMENTAL CHEMOTHERAPY-INDUCED SKIN NECROSIS IN SWINE - MECHANISTIC STUDIES OF ANTHRACYCLINE ANTIBIOTIC TOXICITY AND PROTECTION WITH A RADICAL DIMER COMPOUND  Journal Article
• Epidoxoform: A hydrolytically more stable anthracycline-formaldehyde conjugate toxic to resistant tumor cells  Journal Article
• Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program  Journal Article
• Identification of human intestinal carboxylesterase as the primary enzyme for activation of a doxazolidine carbamate prodrug  Journal Article
• Lack of glutathione conjugation to adriamycin in human breast cancer MCF-7/DOX cells - Inhibition of glutathione S-transferase P1-1 by glutathione conjugates from anthracyclines  Journal Article
• Mass spectrometric measurement of formaldehyde generated in breast cancer cells upon treatment with anthracycline antitumor drugs  Journal Article
• Membrane Stabilization of Biodegradable Polymersomes  Journal Article
• Nuclear targeting and nuclear retention of anthracycline-formaldehyde conjugates implicates DNA covalent bonding in the cytotoxic mechanism of anthracyclines  Journal Article
• PREVENTION OF ADRIAMYCIN TOXICITY  Journal Article
• Perfusion-guided sonopermeation of neuroblastoma: a novel strategy for monitoring and predicting liposomal doxorubicin uptake in vivo  Journal Article
• Preclinical Efficacy of a Carboxylesterase 2-Activated Prodrug of Doxazolidine  Journal Article
• Production of formaldehyde and DNA-adriamycin or DNA-daunomycin adducts, initiated through redox chemistry of dithiothreitol/iron, xanthine oxidase/NADH/iron, or glutathione/iron  Journal Article
• RADICAL DIMER RESCUE OF TOXICITY AND IMPROVED THERAPEUTIC INDEX OF ADRIAMYCIN IN TUMOR-BEARING MICE  Journal Article
• Rational design and synthesis of androgen receptor-targeted nonsteroidal anti-androgen ligands for the tumor-specific delivery of a doxorubicin-formaldehyde conjugate  Journal Article
• Redox pathway leading to the alkylation of DNA by the anthracycline, antitumor drugs adriamycin and daunomycin  Journal Article
• Studies of targeting and intracellular trafficking of an anti-androgen doxorubicin-formaldehyde conjugate in PC-3 prostate cancer cells bearing androgen receptor-GFP chimera  Journal Article
• Supramolecular Stacking of Doxorubicin on Carbon Nanotubes for In Vivo Cancer Therapy  Journal Article
• Synthesis and Biological Characterization of Protease-Activated Prodrugs of Doxazolidine  Journal Article
• The RNase PARN Controls the Levels of Specific miRNAs that Contribute to p53 Regulation  Journal Article
• TiO₂-Capped Gold Nanorods for Plasmon-Enhanced Production of Reactive Oxygen Species and Photothermal Delivery of Chemotherapeutic Agents  Journal Article
• Tumor Necrosis Factor Alpha-Mediated Inflammation and Remodeling of the Extracellular Matrix Underlies Aortic Stiffening Induced by the Common Chemotherapeutic Agent Doxorubicin  Journal Article
• p53 regulates enhancer accessibility and activity in response to DNA damage  Journal Article

broader concept

• Polycyclic Compounds - Daunorubicin  PubMed MeSh Term

narrower concept

• Polycyclic Compounds - Epirubicin  PubMed MeSh Term