Carboxylesterase-2 is a highly sensitive target of the antiobesity agent orlistat with profound implications in the activation of anticancer prodrugs
Journal Article
Overview
publication date
- February 1, 2013
has subject area
- Aminoglycosides - Doxorubicin
- Animals
- Anti-Obesity Agents
- Antineoplastic Agents
- Camptothecin
- Carboxylic Ester Hydrolases
- Cell Line
- Cell Survival
- Drug Interactions
- Female
- Humans
- Hydrocarbons, Aromatic - Doxorubicin
- Irinotecan
- Lactones
- Liver
- Male
- Mice
- Orlistat
- Oxazoles
- Polycyclic Compounds - Doxorubicin
- Prodrugs
- Rats
- Species Specificity
has restriction
- green
Date in CU Experts
- September 3, 2013 3:13 AM
Full Author List
- Xiao D; Shi D; Yang D; Barthel B; Koch TH; Yan B
author count
- 6
citation count
- 31
published in
- Biochemical Pharmacology Journal
Other Profiles
International Standard Serial Number (ISSN)
- 0006-2952
Electronic International Standard Serial Number (EISSN)
- 1873-2968
Digital Object Identifier (DOI)
Additional Document Info
start page
- 439
end page
- 447
volume
- 85
issue
- 3