subject area of
- A Phosphoproteomic Comparison of B-RAF(V600E) and MKK1/2 Inhibitors in Melanoma Cells Journal Article
- Activation of the mitogen-activated protein kinase pathway in U937 leukemic cells induces phosphorylation of the amino terminus of the TATA-binding protein Journal Article
- Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins Journal Article
- Deuterium exchange mass spectrometry as a probe of protein kinase activation. Analysis of wild-type and constitutively active mutants of MAP kinase kinase-1 Journal Article
- ERK1/2 is required for myoblast proliferation but is dispensable for muscle gene expression and cell fusion. Journal Article
- Extracellular signal-regulated kinase activates topoisomerase II alpha through a mechanism independent of phosphorylation Journal Article
- Feedback regulation of Raf-1 and mitogen-activated protein kinase (MAP) kinase kinases 1 and 2 by MAP kinase phosphatase-1 (MKP-1) Journal Article
- Identification of novel MAP kinase pathway signaling targets by functional proteomics and mass spectrometry Journal Article
- Inhibition of mitogen-activated kinase signaling sensitizes HeLa cells to Fas receptor-mediated apoptosis Journal Article
- Interdependent domains controlling the enzymatic activity of mitogen-activated protein kinase kinase 1 Journal Article
- Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization Journal Article
- Leader cell positioning drives wound-directed collective migration in TGF beta-stimulated epithelial sheets Journal Article
- Nuclear localization of mitogen-activated protein kinase kinase 1 (MKK1) is promoted by serum stimulation and G2-M progression - Requirement for phosphorylation at the activation lip and signaling downstream of MKK Journal Article
- Oncogenic B-Raf signaling in melanoma cells controls a network of microRNAs with combinatorial functions Journal Article
- Pharmacologic inhibitors of MKK1 and MKK2 Journal Article
- Phosphorylation of MEK1 by cdk5/p35 down-regulates the mitogen-activated protein kinase pathway Journal Article
- Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells Journal Article
- Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor Journal Article
- Region-specific tolerance to cocaine-regulated cAMP-dependent protein phosphorylation following chronic self-administration Journal Article
- The kinase suppressor of Ras (KSR) modulates growth factor and Ras signaling by uncoupling Elk-1 phosphorylation from MAP kinase activation Journal Article
- The transmembrane molecule kekkon 1 acts in a feedback loop to negatively regulate the activity of the Drosophila EGF receptor during oogenesis Journal Article