A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression
Journal Article
Overview
publication date
- November 10, 2015
has subject area
- Biochemical Phenomena - DNA Replication
- Biochemical Phenomena - Promoter Regions, Genetic
- Biochemical Phenomena - RNA Editing
- CRISPR-Cas Systems
- Carrier Proteins - Telomerase
- Carrier Proteins - Telomerase
- Cell Line - HeLa Cells
- Cellular Structures - Chromosomes
- DNA-Directed DNA Polymerase - Telomerase
- Epithelial Cells - HeLa Cells
- Gene Expression Regulation
- Gene Expression Regulation - RNA Editing
- Genetic Phenomena - DNA Replication
- Genetic Structures - Chromosomes
- Genetic Structures - Promoter Regions, Genetic
- Genetic Structures - Telomere
- Genome, Human
- Humans
- Intranuclear Space - Chromosomes
- Intranuclear Space - Telomere
- Metabolism - RNA Editing
- Mutation
- Nuclear Proteins - Telomerase
- Nucleoproteins - Telomerase
- Regulatory Elements, Transcriptional - Promoter Regions, Genetic
- Tumor Cells, Cultured - HeLa Cells
has restriction
- gold
Date in CU Experts
- November 12, 2015 1:42 AM
Full Author List
- Xi L; Schmidt JC; Zaug AJ; Ascarrunz DR; Cech TR
author count
- 5
citation count
- 71
published in
- Genome Biology Journal
Other Profiles
International Standard Serial Number (ISSN)
- 1474-760X
Digital Object Identifier (DOI)
Additional Document Info
volume
- 16
number
- ARTN 231