Statins Block Calcific Nodule Formation of Valvular Interstitial Cells by Inhibiting alpha-Smooth Muscle Actin Expression
Journal Article
Overview
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Animals
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Aortic Valve
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Calcinosis
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Cell Physiological Phenomena - Cell Proliferation
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Cells, Cultured
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Cytoskeletal Proteins - Actins
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Environment and Public Health - Probability
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Enzyme Inhibitors - Hydroxymethylglutaryl-CoA Reductase Inhibitors
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Fibroblasts
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Gene Expression Regulation
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Gene Transfer Techniques - Transfection
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Growth - Cell Proliferation
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Health Care Evaluation Mechanisms - Probability
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Hydrocarbons, Aromatic - Pravastatin
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Investigative Techniques - Probability
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Lipid Regulating Agents - Hydroxymethylglutaryl-CoA Reductase Inhibitors
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Macromolecular Substances - Actins
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Mathematical Concepts - Probability
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Molecular Mechanisms of Pharmacological Action - Hydroxymethylglutaryl-CoA Reductase Inhibitors
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Muscle Contraction
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Muscle Proteins - Actins
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Musculoskeletal System - Muscle, Smooth
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Nucleic Acids, Nucleotides, and Nucleosides - RNA, Small Interfering
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Polycyclic Compounds - Pravastatin
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RNA - RNA, Small Interfering
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RNA, Small Untranslated - RNA, Small Interfering
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Recombination, Genetic - Transfection
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Reverse Transcriptase Polymerase Chain Reaction
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Swine
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Tissues - Muscle, Smooth
Date in CU Experts
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September 6, 2013 11:56 AM
Full Author List
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Benton JA; Kern HB; Leinwand LA; Mariner PD; Anseth KS
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